Evidence map›Paper›PMID 26874595›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2016

Inequalities in dementia incidence between six racial and ethnic groups over 14 years.

Elizabeth Rose Mayeda, M Maria Glymour, Charles P Quesenberry, Rachel A Whitmer

Registry-linked trialAbstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04426539 (New IDEAS), which is not on this map. Cited by 588 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
588citing papers in PubMed, 8 pooled it
33.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04426539 completednot on this mapstarted 2020, after this paper: background citation

New IDEAS: Imaging Dementia-Evidence for Amyloid Scanning Study - A Study to Improve Precision in Amyloid PET Coverage and Patient Care

Typeobservational_patient_registrySponsorAmerican College of RadiologyRan2020 to 2024Enrolled6,061ConditionsAlzheimer's Disease, Dementia, Mild Cognitive Impairment
3 · Its place in the literature

Who cites it

588 citing papers in PubMed, 8 syntheses or guidelines pooled it, 832 citations in OpenAlex.

  1. Pooled it
  2. Toward compassionate communication: a rapid review on facilitating the dementia disclosure process.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Pooled it
  3. Guideline
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  8. Risk, protective, and biomarkers of dementia in Indigenous peoples: A systematic review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Pooled it
  9. Trial
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  13. Multimorbidity, Polypharmacy, and Neighborhood Disadvantage as Determinants of Cognitive Performance in the ARCHES Cohort.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026
    Article
  14. Article
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  16. Incidence and risk factors for AD/ADRD among American Indian and Alaska Native US Veterans.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  17. Review
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  20. Article

528 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Elizabeth Rose MayedaDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.
M Maria GlymourDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.
Charles P QuesenberryKaiser Permanente Division of Research, Oakland, CA, USA.
Rachel A WhitmerKaiser Permanente Division of Research, Oakland, CA, USA; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA. Electronic address: Rachel.Whitmer@kp.org.
Kaiser Permanente · USUniversity of California, San Francisco · US

Funding

RESOURCE CENTER FOR AGING RESEARCH IN DIVERSE POPULATIONP30AG015272 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEAH S KARLINER · 1997 to 2026
$19.5M
NIA NIH HHS P30 AG015272NIA NIH HHS P30-AG15272
6 · The paper itself

Abstract

introductionReducing racial/ethnic disparities is a primary objective of the National Alzheimer's Plan (NAPA), yet direct comparisons within large samples representing diversity of the United States are lacking.

methodsDementia incidence from January 1, 2000 to December 31, 2013 and a 25-year cumulative risk in 274,283 health care members aged 64+ (n = 18,778 African-American, n = 4543 American Indian/Alaska Native [AIAN], n = 21,000 Latino, n = 440 Pacific Islander, n = 206,490 white, n = 23,032 Asian-Americans). Cox proportional hazard models were adjusted for age, sex, medical utilization, and comorbidities.

resultsDementia incidence (n = 59,555) was highest for African-Americans (26.6/1000 person-years) and AIANs (22.2/1000 person-years); intermediate for Latinos (19.6/1000 person-years), Pacific Islanders (19.6/1000 person-years), and whites (19.3/1000 person-years) and lowest among Asian-Americans (15.2/1000 person-years). Risk was 65% greater for African-Americans (hazard ratio = 1.65; 95% confidence interval = 1.58-1.72) versus Asian-Americans. Cumulative 25-year risk at age 65 was as follows: 38% African-Americans, 35% AIANs, 32% Latino, 25% Pacific Islanders, 30% white, and 28% Asian-Americans. DISCUSSION: Dementia rates varied over 60% between groups, providing a comprehensive benchmark for the NAPA goal of reducing disparities.

Indexed as

AgedAged, 80 and overAge FactorsBlack or African AmericanDelivery of Health CareDementiaEthnicityFemaleHispanic or LatinoHumansIncidenceIndians, North AmericanLongitudinal StudiesMaleMiddle AgedProportional Hazards ModelsCohortDementiaDisparitiesEpidemiologyEthnicityRace

Identifiers

PMID26874595
PMCPMC4969071
OpenAlexW2266863819

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.