ArticleInternational urogynecology journal2016
Pelvic organ prolapse repair using the Uphold™ Vaginal Support System: a 1-year multicenter study.
Article in International urogynecology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 59 citations in OpenAlex.
- Urinary and sexual impact of pelvic reconstructive surgery for genital prolapse by surgical route. A randomized controlled trial.International urogynecology journal · 2022Trial
- Quality-Adjusted Life-Years Outcome 1 Year After Surgery by Robotics-Assisted Sacral Hystero-Colpopexy Versus Vaginal Mesh for Pelvic Organ Prolapse Repair.International urogynecology journal · 2026Article
- Pelvic Organ Prolapse Repair Using Robotic-Assisted Sacral Hysterocolpopexy vs Vaginal Surgery with the Uphold™ System: 1-Year Clinical Outcomes.International urogynecology journal · 2025Article
- Comparison of Early Postoperative Outcomes for Vaginal Anterior Sacrospinous Ligament Fixation with or without Transvaginal Mesh Insertion.Journal of clinical medicine · 2023Article
- Treatment of apical vaginal prolapse with minimal mesh repair (Uphold): patient-reported long-term outcomes and mesh-related complications.Acta obstetricia et gynecologica Scandinavica · 2022Article
- Predictors of Clinical Outcome in Women with Pelvic Organ Prolapse Who Underwent Transvaginal Mesh Reconstruction Surgery.Medicina (Kaunas, Lithuania) · 2022Article
- Association between surgical volumes and real-world healthcare cost when using a mesh capturing device for pelvic organ prolapse: A 5-years comparison between single- versus multicenter use.International urogynecology journal · 2021Article
- Full-thickness vascularized vaginal flap as the fixation point in the surgical treatment of vaginal vault prolapse.International urogynecology journal · 2021Article
- Prospective ultrasonographic follow-up of transvaginal lightweight meshes: a 1-year multicenter study.International urogynecology journal · 2021Observational
- Long-term outcomes of pelvic organ prolapse repair using a mesh-capturing device when comparing single- versus multicenter use.Archives of gynecology and obstetrics · 2021Article
- Stress urinary incontinence after transvaginal mesh surgery for anterior and apical prolapse: preoperative risk factors.International urogynecology journal · 2021Article
- The clinical and urodynamic outcomes of single-incision mesh surgery using the Uphold system for the treatment of pelvic organ prolapse.Scientific reports · 2020Article
- Pelvic organ prolapse and sexual function.Nature reviews. Urology · 2020Review
- A long-term comparative study of Uphold™ transvaginal mesh kit against anterior colporrhaphy.International urogynecology journal · 2020Article
- The resurrection of sacrospinous fixation: unilateral apical sling hysteropexy.International urogynecology journal · 2020Article
- Changes in Sexual Function Following Uphold Transvaginal mesh Surgery for the Treatment of Urogenital Prolapse.Scientific reports · 2019Article
- 1-year outcome after treatment of uterovaginal prolapse with a 6-point fixation mesh.Neurourology and urodynamics · 2019Observational
- A generic health-related quality of life instrument for assessing pelvic organ prolapse surgery: correlation with condition-specific outcome measures.International urogynecology journal · 2018Article
- Short-term outcomes of the transvaginal minimal mesh procedure for pelvic organ prolapse.Investigative and clinical urology · 2018Article
- Comparison of single- versus multicenter outcomes for pelvic organ prolapse repair using a mesh-capturing device.International urogynecology journal · 2018Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisThe objective was to assess safety and clinical outcomes in women operated on using the Uphold™ Lite Vaginal Support System.
methodsWe carried out a 1-year, multicenter, prospective, single cohort study of 207 women with symptomatic Pelvic Organ Prolapse Quantification (POP-Q) stage ≥2 apical pelvic organ prolapse, with or without concomitant anterior vaginal wall prolapse. Safety data were collected using a standardized questionnaire. Anatomical outcome was assessed by the POP-Q and subjective outcomes by the Pelvic Floor Distress Inventory after 2 months and 1 year using a one-way repeated measures analysis of variance. Pain was evaluated using a visual analog scale.
resultsThe overall rate of serious complications was 4.3 % (9 out of 207 patients), including 3 patients with bladder perforations, 1 with bleeding >1,000 ml, 2 who had undergone re-operations with complete mesh removal because of pain, and 3 surgical interventions during follow-up because of mesh exposure. POP-Q stage ≤1 after 1 year was 94 % and subjective symptom relief was reported by 91 % of patients (p < 0.001). Pain after 2 months and 1 year was 60 % lower compared with the preoperative mean (p < 0.001). Minor complications occurred in 20 women (9.7 %) and were dominated by lower urinary tract dysfunction. No predisposing risk factors for complications were found.
conclusionsThe Uphold™ Lite procedure in women with apical pelvic organ prolapse provided satisfactory restoration of vaginal topography and symptom relief. However, serious complication rates were largely comparable with those of other transvaginal mesh kits.
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