Evidence map›Paper›PMID 26874464›Full record

ReviewInternational journal of cancer2016

Roles of N-Myc and STAT interactor in cancer: From initiation to dissemination.

Hawley C Pruitt, Daniel J Devine, Rajeev S Samant

Open access · hybridAbstract readReview
In one paragraph

Review in International journal of cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. N-Myc and STAT Interactor is an Endometriosis Suppressor.International journal of molecular sciences · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Zinc Fingers and Homeobox Family in Cancer: A Double-Edged Sword.International journal of molecular sciences · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Hawley C PruittDepartment of Pathology and Comprehensive Cancer Center, University of Alabama at Birmingham, Alabama, AL.
Daniel J DevineMitchell Cancer Institute, University of South Alabama, AL.
Rajeev S SamantDepartment of Pathology and Comprehensive Cancer Center, University of Alabama at Birmingham, Alabama, AL.
University of Alabama at Birmingham · USUSA Mitchell Cancer Institute · US

Funding

Role of Nmi in retarding breast tumor growth.R01CA140472 · NCI · UNIVERSITY OF SOUTH ALABAMA · PI SAMANT, RAJEEV S · 2010 to 2014
$1.3M
NCI NIH HHS R01 CA140472
6 · The paper itself

Abstract

N-myc & STAT Interactor, NMI, is a protein that has mostly been studied for its physical interactions with transcription factors that play critical roles in tumor growth, progression and metastasis. NMI is an inducible protein, thus its intracellular levels and location can vary dramatically, influencing a diverse array of cellular functions in a context-dependent manner. The physical interactions of NMI with its binding partners have been linked to many aspects of tumor biology including DNA damage response, cell death, epithelial-to-mesenchymal transition and stemness. Thus, discovering more details about the function(s) of NMI could reveal key insights into how transcription factors like c-Myc, STATs and BRCA1 are contextually regulated. Although a normal, physiological function of NMI has not yet been discovered, it has potential roles in pathologies ranging from viral infection to cancer. This review provides a timely perspective of the unfolding roles of NMI with specific focus on cancer progression and metastasis.

Indexed as

AnimalsCell Transformation, NeoplasticDisease ProgressionGene Expression Regulation, NeoplasticHumansIntracellular Signaling Peptides and ProteinsNeoplasm MetastasisNeoplasmsProtein BindingSignal TransductionIntracellular Signaling Peptides and ProteinsNMI protein, humancancerN-myc interactortranscription

Identifiers

PMID26874464
PMCPMC5069610
OpenAlexW2255988484

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.