Evidence map›Paper›PMID 26874367›Full record

Trial reportThe Journal of allergy and clinical immunology2016

Vitamin D3 treatment of vitamin D-insufficient asthmatic patients does not alter immune cell function.

Brandy Reid, Pierre-Olivier Girodet, Jonathan S Boomer, Azza Abdel-Gadir, Kathy Zheng, Michael E Wechsler, Leonard B Bacharier, Susan J Kunselman, Tonya S King, Elliot Israel and 3 more

Abstract readLetterRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of allergy and clinical immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Vitamin D for the management of asthma.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Vitamin D for the management of asthma.The Cochrane database of systematic reviews · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Brandy ReidDepartment of Internal Medicine, Washington University School of Medicine, St Louis, Mo.
Pierre-Olivier GirodetDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass; University of Bordeaux, Centre de Recherche Cardio-thoracique de Bordeaux, Département de Pharmacologie, Bordeaux, France.
Jonathan S BoomerDepartment of Internal Medicine, Washington University School of Medicine, St Louis, Mo.
Azza Abdel-GadirDivision of Immunology, Boston Children's Hospital, Boston, Mass.
Kathy ZhengDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.
Michael E WechslerDepartment of Medicine, National Jewish Health, Denver, Colo.
Leonard B BacharierDepartment of Pediatrics, Washington University School of Medicine, St Louis, Mo.
Susan J KunselmanDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pa.
Tonya S KingDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pa.
Elliot IsraelDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.
Mario CastroDepartment of Internal Medicine, Washington University School of Medicine, St Louis, Mo.
Manuela CernadasDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.
Jonathan M GreenDepartment of Internal Medicine, Washington University School of Medicine, St Louis, Mo; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Mo. Electronic address: jgreen@wustl.edu.

Funding

Data Coordinating Center for the NHLBI Asthma Network (AsthmaNet)U10HL098115 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MAUGER, DAVID T. · 2009 to 2015
$57.6M
PEDIATRIC ASTHMA NETWORK DATA COORDINATING CENTERU10HL064313 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MAUGER, DAVID T. · 1999 to 2008
$18.3M
AsthmaNet: Brigham and Women's Hospital & Children's Hospital BostonU10HL098102 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ISRAEL, ELLIOT, PHIPATANAKUL, WANDA · 2009 to 2015
$5.5M
Clinical Centers for the NHLBI Asthma Network (AsthmaNet)U10HL098075 · NHLBI · NATIONAL JEWISH HEALTH · PI SZEFLER, STANLEY J., WECHSLER, MICHAEL E · 2009 to 2015
$5.1M
NHLBI NIH HHS U10 HL064313NHLBI NIH HHS U10 HL098075NHLBI NIH HHS U10 HL098102NHLBI NIH HHS U10 HL098115
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adrenal Cortex HormonesAsthmaCD4-Positive T-LymphocytesCholecalciferolDendritic CellsGene ExpressionHumansInterferon-gammaInterleukinsMonocytesTransforming Growth Factor betaTumor Necrosis Factor-alphaVitamin D DeficiencyAdrenal Cortex HormonesCholecalciferolIFNG protein, humanInterferon-gammaInterleukinsTransforming Growth Factor betaTumor Necrosis Factor-alpha

Identifiers

PMID26874367
PMCPMC4931954

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.