Evidence map›Paper›PMID 26874219›Full record

ReviewTranslational research : the journal of laboratory and clinical medicine2016

Neuroimaging with magnetoencephalography: A dynamic view of brain pathophysiology.

Tony W Wilson, Elizabeth Heinrichs-Graham, Amy L Proskovec, Timothy J McDermott

Abstract readReview
In one paragraph

Review in Translational research : the journal of laboratory and clinical medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 103 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Frontier and hot topics in Magnetoencephalography(MEG) in neurological diseases.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Oscillatory Dynamics Serving Verbal Working Memory Differ in People with HIV and Are Linked To Disease Duration.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Article
  13. Motor-Related Neural Dynamics are Modulated by Regular Cannabis Use Among People with HIV.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Article
  14. Oscillatory brain dynamics underlying affective face processing.Social cognitive and affective neuroscience · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Tony W WilsonDepartment of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center (UNMC), Omaha, Neb; Center for Magnetoencephalography, UNMC, Omaha, Neb; Department of Neurological Sciences, UNMC, Omaha, Neb. Electronic address: tony.w.wilson@gmail.com.
Elizabeth Heinrichs-GrahamDepartment of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center (UNMC), Omaha, Neb; Center for Magnetoencephalography, UNMC, Omaha, Neb.
Amy L ProskovecCenter for Magnetoencephalography, UNMC, Omaha, Neb; Department of Psychology, University of Nebraska - Omaha, Neb.
Timothy J McDermottDepartment of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center (UNMC), Omaha, Neb; Center for Magnetoencephalography, UNMC, Omaha, Neb.
University of Nebraska Medical Center · USNebraska Medical Center · USUniversity of Nebraska at Omaha · US

Funding

Neurophysiological markers of HAND and the impact of aging: Evidence from MEGR01MH103220 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WILSON, TONY W · 2014 to 2018
$2.5M
NIMH NIH HHS R01 MH103220
6 · The paper itself

Abstract

Magnetoencephalography (MEG) is a noninvasive, silent, and totally passive neurophysiological imaging method with excellent temporal resolution (∼1 ms) and good spatial precision (∼3-5 mm). In a typical experiment, MEG data are acquired as healthy controls or patients with neurologic or psychiatric disorders perform a specific cognitive task, or receive sensory stimulation. The resulting data are generally analyzed using standard electrophysiological methods, coupled with advanced image reconstruction algorithms. To date, the total number of MEG instruments and associated users is significantly smaller than comparable human neuroimaging techniques, although this is likely to change in the near future with advances in the technology. Despite this small base, MEG research has made a significant impact on several areas of translational neuroscience, largely through its unique capacity to quantify the oscillatory dynamics of activated brain circuits in humans. This review focuses on the clinical areas where MEG imaging has arguably had the greatest impact in regard to the identification of aberrant neural dynamics at the regional and network level, monitoring of disease progression, determining how efficacious pharmacologic and behavioral interventions modulate neural systems, and the development of neural markers of disease. Specifically, this review covers recent advances in understanding the abnormal neural oscillatory dynamics that underlie Parkinson's disease, autism spectrum disorders, human immunodeficiency virus (HIV)-associated neurocognitive disorders, cerebral palsy, attention-deficit hyperactivity disorder, cognitive aging, and post-traumatic stress disorder. MEG imaging has had a major impact on how clinical neuroscientists understand the brain basis of these disorders, and its translational influence is rapidly expanding with new discoveries and applications emerging continuously.

Indexed as

AgingAnimalsBrainHumansMagnetoencephalographyNervous System DiseasesNeuroimaging

Identifiers

PMID26874219
PMCPMC4959997
OpenAlexW2251616250

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.