Evidence map›Paper›PMID 26873685›Full record

ArticleJournal of the American Heart Association2016

Rates of Atrial Fibrillation in Black Versus White Patients With Pacemakers.

Hooman Kamel, Dawn O Kleindorfer, Prashant D Bhave, Mary Cushman, Emily B Levitan, George Howard, Elsayed Z Soliman

Open access · goldAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

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  19. Prevalence and predictors of atrial arrhythmias in patients with sinus node dysfunction and atrial pacing.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2018
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Hooman KamelDepartment of Neurology and Feil Family Brain and Mind Research Institute, Weill Cornell Medical College, New York, NY hok9010@med.cornell.edu.
Dawn O KleindorferDepartment of Neurology, University of Cincinnati, OH.
Prashant D BhaveDivision of Cardiology, University of Iowa Carver College of Medicine, Iowa City, IA.
Mary CushmanDepartments of Medicine and Pathology, Cardiovascular Research Institute, University of Vermont, Burlington, VT.
Emily B LevitanDepartment of Epidemiology, University of Alabama at Birmingham, AL.
George HowardDepartment of Biostatistics, University of Alabama at Birmingham, AL.
Elsayed Z SolimanEpidemiological Cardiology Research Center, Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC Department of Internal Medicine-Cardiology, Wake Forest School of Medicine, Winston-Salem, NC.
University of Alabama at Birmingham · USMIND Research Institute · USUniversity of Cincinnati · USUniversity of Iowa · USUniversity of Vermont · USWake Forest University · US

Funding

Atrial Fibrillation Precursors May Be Novel Stroke Risk FactorsK23NS082367 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI KAMEL, HOOMAN · 2013 to 2017
$937k
NINDS NIH HHS K23 NS082367NINDS NIH HHS K23NS082367
6 · The paper itself

Abstract

backgroundBlack US residents experience higher rates of ischemic stroke than white residents but have lower rates of clinically apparent atrial fibrillation (AF), a strong risk factor for stroke. It is unclear whether black persons truly have less AF or simply more undiagnosed AF. METHODS AND

resultsWe obtained administrative claims data from state health agencies regarding all emergency department visits and hospitalizations in California, Florida, and New York. We identified a cohort of patients with pacemakers, the regular interrogation of which reduces the likelihood of undiagnosed AF. We compared rates of documented AF or atrial flutter at follow-up visits using Kaplan-Meier survival statistics and Cox proportional hazards models adjusted for demographic characteristics and vascular risk factors. We identified 10 393 black and 91 380 white patients without documented AF or atrial flutter before or at the index visit for pacemaker implantation. During 3.7 (±1.8) years of follow-up, black patients had a significantly lower rate of AF (21.4%; 95% CI 19.8-23.2) than white patients (25.5%; 95% CI 24.9-26.0). After adjustment for demographic characteristics and comorbidities, black patients had a lower hazard of AF (hazard ratio 0.91; 95% CI 0.86-0.96), a higher hazard of atrial flutter (hazard ratio 1.29; 95% CI 1.11-1.49), and a lower hazard of the composite of AF or atrial flutter (hazard ratio 0.94; 95% CI 0.88-99).

conclusionsIn a population-based sample of patients with pacemakers, black patients had a lower rate of AF compared with white patients. These findings indicate that the persistent racial disparities in rates of ischemic stroke are likely to be related to factors other than undiagnosed AF.

Indexed as

Black or African AmericanCardiac Pacing, ArtificialHealth Status DisparitiesPacemaker, ArtificialWhite PeopleAgedAged, 80 and overAtrial FibrillationAtrial FlutterElectrocardiographyFemaleHumansKaplan-Meier EstimateMaleMiddle AgedPredictive Value of Testsatrial fibrillationatrial flutterepidemiologyrisk factorsstroke

Identifiers

PMID26873685
PMCPMC4802468
OpenAlexW2290635076

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.