ArticleJournal of the American Heart Association2016
Metabolic Syndrome in Adults With Congenital Heart Disease.
Article in Journal of the American Heart Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
52 citing papers in PubMed, 2 syntheses or guidelines pooled it, 108 citations in OpenAlex.
- Decreased lipid levels in adult with congenital heart disease: a systematic review and Meta-analysis.BMC cardiovascular disorders · 2023Pooled it
- Overweight and Obesity in Patients with Congenital Heart Disease: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Anti-obesity medications in adults with congenital heart disease: a comprehensive review and expert clinical recommendations.European heart journal. Quality of care & clinical outcomes · 2026Review
- The impact of psychosocial factors on secondary hyperparathyroidism and vitamin D deficiency in adults with congenital heart disease-the CHD-HYPER study.Frontiers in nutrition · 2026Article
- Are We Always Prepared for Urgent Coronary Interventions in Complex Adult Congenital Heart Disease Patients?Case reports in cardiology · 2026Article
- Transition from Paediatric to Adult Care in Congenital Heart Disease: A Call for Action.Journal of clinical medicine · 2025Review
- Cardiological rehabilitation, prehabilitation, and cardiovascular prevention in adults with congenital heart defects: tasks and services of the German Pension Insurance-part 1: preventive cardiology and prehabilitation.Cardiovascular diagnosis and therapy · 2025Review
- Overweight and Obesity in Adults with Congenital Heart Disease and Heart Failure: Real-World Evidence from the PATHFINDER-CHD Registry.Journal of clinical medicine · 2025Article
- Beyond the Scale: The Hidden Burden of Underweight and Cachexia in Adults with Congenital Heart Defects and Heart Failure-Results from the Pathfinder CHD-Registry.Journal of clinical medicine · 2025Article
- Risk of malignancy in adult patients with congenital heart disease: a clinical practice review.Cardiovascular diagnosis and therapy · 2025Review
- Congenital Heart Disease After Mid-Age: From the "Grown-Up" to the Elderly.Diagnostics (Basel, Switzerland) · 2025Review
- Transitional Care for Adult Patients with Congenital Heart Disease.Internal medicine (Tokyo, Japan) · 2025Review
- Atherosclerotic Risk Factor Prevalence in Adults With Congenital Heart Disease: A Meta-Analysis.JACC. Advances · 2024Article
- Development and Validation of a Mortality Risk Score for Repaired Tetralogy of Fallot.Journal of the American Heart Association · 2024Article
- Access to Specialized Care Across the Lifespan in Tetralogy of Fallot.CJC pediatric and congenital heart disease · 2023Review
- Prognosis of Chronic Kidney Disease and Metabolic Syndrome in Adults With Congenital Heart Disease.Journal of Korean medical science · 2023Article
- Cardiometabolic Risk Factors in Mexican Adults With Congenital Heart Disease.JACC. Advances · 2023Article
- Coronary artery disease in adults with congenital heart disease.International journal of cardiology. Congenital heart disease · 2023Review
- Nutrition, dietary recommendations, and supplements for patients with congenital heart disease.International journal of cardiology. Congenital heart disease · 2023Review
- Association of Body Mass Index With Clinical Features and Outcomes in Adults With Fontan Palliation.Journal of the American Heart Association · 2023Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMetabolic syndrome increases risk for atherosclerotic coronary artery disease, and its prevalence increases with increasing age and body mass index. Adults with congenital heart disease (ACHD) are now living longer and accruing coronary artery disease risk factors. However, the prevalence of metabolic syndrome in ACHD patients is unknown. METHODS AND
resultsWe conducted a retrospective cohort study of ACHD patients at our center to quantify the prevalence of metabolic syndrome in an ACHD population. Using case-control matching, we constructed a comparable control group from a population-based sample of 150 104 adults. International Diabetes Federation criteria were used to define metabolic syndrome. We used logistic regression to compare the risk of metabolic syndrome across the resulting cohorts, which were composed of 448 ACHD patients and 448 controls matched by age and sex. Mean age of both groups was 32.4±11.3 years, and 51.3% were female. Obesity was present in 16.1% of the ACHD patients and 16.7% of the controls. Metabolic syndrome was more common in ACHD patients than in controls (15.0% versus 7.4%; odds ratio 1.82, 95% CI 1.25-2.65).
conclusionsOur data suggest that metabolic syndrome is more common among adults with congenital heart disease than in the general population. Thus, patients with congenital heart disease should be screened for metabolic syndrome and risk factors mitigated where possible to prevent atherosclerotic coronary artery disease. Preventive cardiology should be included during routine ACHD care.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.