ArticleEuropean radiology2016
Diffusion weighted imaging in cystic fibrosis disease: beyond morphological imaging.
Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- State-of-the-art review of lung imaging in cystic fibrosis with recommendations for pulmonologists and radiologists from the "iMAging managEment of cySTic fibROsis" (MAESTRO) consortium.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- The use of chest magnetic resonance imaging in interstitial lung disease: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2018Pooled it
- A preliminary evaluation of chest magnetic resonance imaging in adult patients with non-cystic fibrosis bronchiectasis.La Radiologia medica · 2026Article
- MDCT and MRI in Bronchiectasis in Older Children and Young Adults - A Non-Inferiority Trial.Indian journal of pediatrics · 2025Article
- Application of low-dose FDG-PET/MRI for quantification of lung changes in pediatric patients with cystic fibrosis: a new inflammatory index.Quantitative imaging in medicine and surgery · 2025Article
- Chest magnetic resonance imaging in cystic fibrosis: technique and clinical benefits.Pediatric radiology · 2023Review
- Lung and large airway imaging: magnetic resonance imaging versus computed tomography.Pediatric radiology · 2022Review
- Management of respiratory tract exacerbations in people with cystic fibrosis: Focus on imaging.Frontiers in pediatrics · 2022Review
- Cross-sectional analysis of follow-up chest MRI and chest CT scans in patients previously affected by COVID-19.La Radiologia medica · 2021Article
- Molecular Imaging of Pulmonary Inflammation and Infection.International journal of molecular sciences · 2020Review
- Lung function imaging methods in Cystic Fibrosis pulmonary disease.Respiratory research · 2017Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo explore the feasibility of diffusion-weighted imaging (DWI) to assess inflammatory lung changes in patients with Cystic Fibrosis (CF)
methodsCF patients referred for their annual check-up had spirometry, chest-CT and MRI on the same day. MRI was performed in a 1.5 T scanner with BLADE and EPI-DWI sequences (b = 0-600 s/mm
resultsThirty-three CF patients were enrolled (mean 21 years, range 6-51, 19 female). 4 % (SD 2.6, range 1.5-12.9) of total CF-CT alterations presented DWI-hotspots. DWI-hotspots coincided with mucus plugging (60 %), consolidation (30 %) and bronchiectasis (10 %). DWI
conclusionsDWI-hotspots strongly correlated with radiological and clinical parameters of lung disease severity. Future validation studies are needed to establish the exact nature of DWI-hotspots in CF patients. KEY POINTS: • DWI hotspots only partly overlapped structural abnormalities on morphological imaging • DWI strongly correlated with radiological and clinical indicators of CF-disease severity • Patients with more DWI hotspots had lower lung function values • Mucus score best predicted the presence of DWI-hotspots with restricted diffusion.
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