Evidence map›Paper›PMID 26873490›Full record

ReviewTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2016

The potential role of CacyBP/SIP in tumorigenesis.

Xiaoxuan Ning, Yang Chen, Xiaosu Wang, Qiaoneng Li, Shiren Sun

Abstract readReview
PubMed Publisher
In one paragraph

Review in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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  7. Cysteine Proteases fromInternational journal of molecular sciences · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xiaoxuan NingDepartment of Geriatrics, Xi Jing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China. ningxx01@fmmu.edu.cn.
Yang ChenDepartment of Geriatrics, Xi Jing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Xiaosu WangDepartment of Geriatrics, Xi Jing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Qiaoneng LiDepartment of Geriatrics, Xi Jing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Shiren SunDepartment of Nephrology, Xi Jing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China. ningsun@fmmu.edu.cn.
Air Force Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcyclin-binding protein/Siah-1-interacting protein (CacyBP/SIP) was initially described as a binding partner of S100A6 in the Ehrlich ascites tumor cells and later as a Siah-1-interacting protein. This 30 kDa protein includes three domains and is involved in cell proliferation, differentiation, cytoskeletal rearrangement, and transcriptional regulation via binding to various proteins. Studies have also shown that the CacyBP/SIP is a critical protein in tumorigenesis. But, its promotion or suppression of cancer progression may depend on the cell type. In this review, the biological characteristics and target proteins of CacyBP/SIP have been described. Moreover, the exact role of CacyBP/SIP in various cancers is discussed.

Indexed as

Cell Transformation, NeoplasticAnimalsbeta CateninCalcium-Binding ProteinsCarcinoma, Ehrlich TumorCell Line, TumorCytoskeletal ProteinsDrug Resistance, MultipleDrug Resistance, NeoplasmExtracellular Signal-Regulated MAP KinasesHumansNeoplasm ProteinsNeoplasmsS100 ProteinsUbiquitin-Protein Ligase Complexesbeta CateninCACYBP protein, humanCacybp protein, mouseCalcium-Binding ProteinsCytoskeletal ProteinsExtracellular Signal-Regulated MAP KinasesNeoplasm ProteinsS100 ProteinsUbiquitin-Protein Ligase ComplexesCacyBP/SIPMultidrug resistanceTumorigenesisβ-Catenin

Identifiers

PMID26873490
OpenAlexW2263906180

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.