Evidence map›Paper›PMID 26873392›Full record

Trial reportJournal of evidence-based complementary & alternative medicine2017

Effectiveness of Anise Oil for Treatment of Mild to Moderate Depression in Patients With Irritable Bowel Syndrome: A Randomized Active and Placebo-Controlled Clinical Trial.

Maryam Mosaffa-Jahromi, Ali-Mohammad Tamaddon, Suleiman Afsharypuor, Alireza Salehi, Seyed Hassan Seradj, Mehdi Pasalar, Peyman Jafari, Kamran Bagheri Lankarani

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of evidence-based complementary & alternative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Article
  3. Emerging Biopharmaceuticals fromMolecules (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Maryam Mosaffa-JahromiDepartment of Traditional Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Ali-Mohammad TamaddonCenter for Nanotechnology in Drug Delivery and Department of Pharmaceutics, Shiraz University of Medical Sciences, Shiraz, Iran.
Suleiman AfsharypuorDepartment of Pharmacognosy, School of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran.
Alireza SalehiResearch Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Seyed Hassan SeradjDepartment of Pharmacognosy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Mehdi PasalarResearch Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Pasalar@sums.ac.ir tamaddon@sums.ac.ir.
Peyman JafariDepartment of Biostatistics, Shiraz University of Medical Sciences, Shiraz, Iran.
Kamran Bagheri LankaraniHealth Policy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz University of Medical Sciences · IRIsfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is a prevalent disorder among patients suffering from irritable bowel syndrome. The current study was performed to evaluate the effect of a traditional Persian medicine product, anise oil, in removing the symptoms of mild to moderate depression in patients with irritable bowel syndrome. In a randomized double-blinded active and placebo controlled clinical trial, 120 participants with mild to moderate depression according to the Beck Depression Inventory-II total scores were categorized into 3 equal groups and received anise oil, Colpermin, and placebo. The results at the end of trial (week 4) and follow-up (week 6) demonstrated significant priority against active and placebo groups. Although the mechanism is unknown yet, anise oil could be a promising choice of treatment for depressed patients with irritable bowel syndrome.

Indexed as

PimpinellaAdultDepressionFemaleHumansIrritable Bowel SyndromeMaleMedicine, ArabicMiddle AgedOils, VolatilePlant OilsYoung AdultOils, VolatilePlant Oilsanisedepressionirritable bowel syndrometraditional Persian medicine

Identifiers

PMID26873392
PMCPMC5871202
OpenAlexW2284730489

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.