Evidence map›Paper›PMID 26872821›Full record

ArticleVeterinary research2016

Large genomic differences between Moraxella bovoculi isolates acquired from the eyes of cattle with infectious bovine keratoconjunctivitis versus the deep nasopharynx of asymptomatic cattle.

Aaron M Dickey, John D Loy, James L Bono, Timothy P L Smith, Mike D Apley, Brian V Lubbers, Keith D DeDonder, Sarah F Capik, Robert L Larson, Brad J White and 3 more

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
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  18. Frontiers in veterinary science · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Aaron M DickeyUnited States Department of Agriculture (USDA), Agricultural Research Service (ARS), U.S. Meat Animal Research Center (USMARC), State Spur 18D, Clay Center, NE, 68933, USA. aaron.dickey@ars.usda.gov.
John D LoySchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE, 68583-0907, USA. jdloy@unl.edu.
James L BonoUnited States Department of Agriculture (USDA), Agricultural Research Service (ARS), U.S. Meat Animal Research Center (USMARC), State Spur 18D, Clay Center, NE, 68933, USA. jim.bono@ars.usda.gov.
Timothy P L SmithUnited States Department of Agriculture (USDA), Agricultural Research Service (ARS), U.S. Meat Animal Research Center (USMARC), State Spur 18D, Clay Center, NE, 68933, USA. tim.smith@ars.usda.gov.
Mike D ApleyCollege of Veterinary Medicine, Kansas State University, Manhattan, KS, 66506, USA. mapley@vet.k-state.edu.
Brian V LubbersKansas State Diagnostic Laboratory, Kansas State University, Manhattan, KS, 66506, USA. blubbers@k-state.edu.
Keith D DeDonderCollege of Veterinary Medicine, Kansas State University, Manhattan, KS, 66506, USA. kdd5257@vet.k-state.edu.
Sarah F CapikCollege of Veterinary Medicine, Kansas State University, Manhattan, KS, 66506, USA. scapik@vet.k-state.edu.
Robert L LarsonCollege of Veterinary Medicine, Kansas State University, Manhattan, KS, 66506, USA. rlarson@vet.k-state.edu.
Brad J WhiteCollege of Veterinary Medicine, Kansas State University, Manhattan, KS, 66506, USA. bwhite@vet.k-state.edu.
Jochen BlomBioinformatics and Systems Biology, Justus-Liebig-University Giessen, 35392, Giessen, Germany. Jochen.Blom@computational.bio.uni-giessen.de.
Carol G Chitko-McKownUnited States Department of Agriculture (USDA), Agricultural Research Service (ARS), U.S. Meat Animal Research Center (USMARC), State Spur 18D, Clay Center, NE, 68933, USA. carol.chitkomckown@ars.usda.gov.
Michael L ClawsonUnited States Department of Agriculture (USDA), Agricultural Research Service (ARS), U.S. Meat Animal Research Center (USMARC), State Spur 18D, Clay Center, NE, 68933, USA. mike.clawson@ars.usda.gov.
Kansas State University · USUnited States Department of Agriculture · USAgricultural Research Service · USRoman L. Hruska U.S. Meat Animal Research Center · USUniversity of Giessen · DEUniversity of Nebraska–Lincoln · US

Funding

Nebraska Center for VirologyP30GM103509 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 2012 to 2014
$3.3M
NIGMS NIH HHS P30 GM103509
6 · The paper itself

Abstract

Moraxella bovoculi is a recently described bacterium that is associated with infectious bovine keratoconjunctivitis (IBK) or "pinkeye" in cattle. In this study, closed circularized genomes were generated for seven M. bovoculi isolates: three that originated from the eyes of clinical IBK bovine cases and four from the deep nasopharynx of asymptomatic cattle. Isolates that originated from the eyes of IBK cases profoundly differed from those that originated from the nasopharynx of asymptomatic cattle in genome structure, gene content and polymorphism diversity and consequently placed into two distinct phylogenetic groups. These results suggest that there are genetically distinct strains of M. bovoculi that may not associate with IBK.

Indexed as

AnimalsBacterial ProteinsCattleCattle DiseasesEyeKeratoconjunctivitisMolecular Sequence DataMoraxellaMoraxellaceae InfectionsNasopharynxPhylogenySequence Analysis, DNABacterial Proteins

Identifiers

PMID26872821
PMCPMC4752781
OpenAlexW2273640282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.