ArticleJournal of bacteriology1989
Nucleotide sequences of the tolA and tolB genes and localization of their products, components of a multistep translocation system in Escherichia coli.
Article in Journal of bacteriology, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 88 citations in OpenAlex.
- Antibacterial toxin colicin N and phage protein G3p compete with TolB for a binding site on TolA.Microbiology (Reading, England) · 2015Article
- The crystal structure of the TolB box of colicin A in complex with TolB reveals important differences in the recruitment of the common TolB translocation portal used by group A colicins.Molecular microbiology · 2010Article
- Interactions of the energy transducer TonB with noncognate energy-harvesting complexes.Journal of bacteriology · 2008Article
- Selection for highly biased amino acid frequency in the TolA cell envelope protein of Proteobacteria.Journal of molecular evolution · 2003Article
- Characterization of divIVA and other genes located in the chromosomal region downstream of the dcw cluster in Streptococcus pneumoniae.Journal of bacteriology · 2003Article
- RNA degradosomes exist in vivo in Escherichia coli as multicomponent complexes associated with the cytoplasmic membrane via the N-terminal region of ribonuclease E.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Comparison of the Escherichia coli K-12 genome with sampled genomes of a Klebsiella pneumoniae and three salmonella enterica serovars, Typhimurium, Typhi and Paratyphi.Nucleic acids research · 2000Article
- A genomic sample sequence of the entomopathogenic bacterium Photorhabdus luminescens W14: potential implications for virulence.Applied and environmental microbiology · 2000Article
- The phage infection process: a functional role for the distal linker region of bacteriophage protein 3.Journal of virology · 2000Article
- RegA, iron, and growth phase regulate expression of the Pseudomonas aeruginosa tol-oprL gene cluster.Journal of bacteriology · 2000Article
- The adsorption protein genes of Xanthomonas campestris filamentous phages determining host specificity.Journal of bacteriology · 1999Article
- Colicin import into Escherichia coli cells.Journal of bacteriology · 1998Review
- Linkage map of Escherichia coli K-12, edition 10: the traditional map.Microbiology and molecular biology reviews : MMBR · 1998Review
- At least four percent of the Salmonella typhimurium genome is required for fatal infection of mice.Infection and immunity · 1998Article
- The TolQRA proteins are required for membrane insertion of the major capsid protein of the filamentous phage f1 during infection.Journal of bacteriology · 1998Article
- Filamentous phage infection: required interactions with the TolA protein.Journal of bacteriology · 1997Article
- The TolA protein interacts with colicin E1 differently than with other group A colicins.Journal of bacteriology · 1997Article
- Characterization of the tol-pal and cyd region of Escherichia coli K-12: transcript analysis and identification of two new proteins encoded by the cyd operon.Journal of bacteriology · 1997Article
- Characterization of an OprL null mutant of Pseudomonas putida.Journal of bacteriology · 1996Article
- Haemonchus contortus GA1 antigens: related, phospholipase C-sensitive, apical gut membrane proteins encoded as a polyprotein and released from the nematode during infection.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Various mutations in the tolQRAB gene cluster of Escherichia coli render the bacteria tolerant to high concentrations of the E, A, or K colicins as well as tolerant to infection by the single-stranded filamentous bacteriophage. The nucleotide sequence of a 2.8-kilobase fragment containing the tolA and tolB genes was determined. This sequence predicts TolA to be a 421-amino-acid protein of molecular mass 44,190 daltons. Studies using minicells show it to be associated with the inner membrane, presumably via a 21-amino-acid hydrophobic sequence between residues 13 and 35. The remaining 387 residues on the carboxyl side of this region are located in the periplasm. Within this region of TolA is a 230-residue portion that is predicted to form a very long helical segment. This region is rich in alanine, lysine, and glutamic and aspartic acids. The TolB protein is predicted to contain 431 amino acids. Localization studies using minicells show two proteins encoded by this open reading frame. The larger protein of 47.5 kilodaltons appears to be associated with the membrane fractions. The smaller protein is 43 kilodaltons in size and is found with the periplasmic components of the cell.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.