SynthesisPloS one2016
Mortality Patterns in Patients with Multiple Trauma: A Systematic Review of Autopsy Studies.
Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effect of tranexamic acid by baseline risk of death in acute bleeding patients: a meta-analysis of individual patient-level data from 28 333 patients.British journal of anaesthesia · 2020Pooled it
- Are Pre-hospital Trauma Deaths Preventable? A Systematic Literature Review.World journal of surgery · 2019Pooled it
- Point-of-care ultrasonography for diagnosing thoracoabdominal injuries in patients with blunt trauma.The Cochrane database of systematic reviews · 2018Pooled it
- Comparison of two viscoelastic devices in patients with severe trauma: a prospective observational study.Scientific reports · 2026Observational
- Oestradiol dynamics after polytrauma are linked to injury severity and adverse outcomes.Frontiers in endocrinology · 2026Article
- Adolescent trauma and alcohol: increased risk for severe head injury and organ dysfunction-insights from the TraumaRegister DGUEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- Polytrauma-related deaths in Moscow: Retrospective analysis of 969 autopsy studies.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025Article
- Bimodal, But Not the Same: Persistent Late Peaks in Trauma Mortality.World journal of surgery · 2025Article
- Injury patterns and patient outcomes of abdominal trauma in the elderly population: a 5-year experience of a Major Trauma Centre.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- Limited Diagnostic Value of miRNAs in Early Trauma-Induced Liver Injury: Only miRNA-122 Emerges as a Late-Phase Marker.Diagnostics (Basel, Switzerland) · 2025Article
- Traumatic Brain Injury as a Public Health Issue: Epidemiology, Prognostic Factors and Useful Data from Forensic Practice.Healthcare (Basel, Switzerland) · 2024Review
- The Ambivalent Role of miRNA-21 in Trauma and Acute Organ Injury.International journal of molecular sciences · 2024Review
- Development and validation of a machine learning-based model to assess probability of systemic inflammatory response syndrome in patients with severe multiple traumas.BMC medical informatics and decision making · 2024Observational
- Prehospital time and mortality in pediatric trauma.Pediatric surgery international · 2024Article
- Injury characteristics and mortality in an emergency department in Ethiopia: a single-center observational study.BMC emergency medicine · 2024Observational
- Percutaneous ultrasound-guided versus open cut-down access to femoral vessels for the placement of a REBOA catheter.Scientific reports · 2024Observational
- Torso hemorrhage: noncompressible? never say never.European journal of medical research · 2024Review
- Independent predictors of mortality for critically ill patients with polytrauma: A single center, retrospective study.Heliyon · 2024Article
- Preventable trauma deaths in the Western Cape of South Africa: A consensus-based panel review.PLOS global public health · 2024Article
- Identification of novel blood-based extracellular vesicles biomarker candidates with potential specificity for traumatic brain injury in polytrauma patients.Frontiers in immunology · 2024Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeA high percentage (50%-60%) of trauma patients die due to their injuries prior to arrival at the hospital. Studies on preclinical mortality including post-mortem examinations are rare. In this review, we summarized the literature focusing on clinical and preclinical mortality and studies included post-mortem examinations.
methodsA literature search was conducted using PubMed/Medline database for relevant medical literature in English or German language published within the last four decades (1980-2015). The following MeSH search terms were used in different combinations: "multiple trauma", "epidemiology", "mortality ", "cause of death", and "autopsy". References from available studies were searched as well.
resultsMarked differences in demographic parameters and injury severity between studies were identified. Moreover, the incidence of penetrating injuries has shown a wide range (between 4% and 38%). Both unimodal and bimodal concepts of trauma mortality have been favored. Studies have shown a wide variation in time intervals used to analyze the distribution of death. Thus, it is difficult to say which distribution is correct.
conclusionsWe have identified variable results indicating bimodal or unimodal death distribution. Further more stundardized studies in this field are needed. We would like to encourage investigators to choose the inclusion criteria more critically and to consider factors affecting the pattern of mortality.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.