SynthesisMedicine2016
Complementary and Alternative Medicine Treatment Options for Otitis Media: A Systematic Review.
Synthesis in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Comparative efficacy of different probiotic strains and preparations for prevention of acute otitis media in children: a systematic review and network meta-analysis.Frontiers in nutrition · 2026Pooled it
- Homeopathic medicinal products for preventing and treating acute respiratory tract infections in children.The Cochrane database of systematic reviews · 2022Pooled it
- Homeopathic medicinal products for preventing and treating acute respiratory tract infections in children.The Cochrane database of systematic reviews · 2018Pooled it
- Homeopathic medicinal products for preventing and treating acute respiratory tract infections in children.The Cochrane database of systematic reviews · 2018Pooled it
- Topical administration of hyaluronic acid in children with recurrent or chronic middle ear inflammations.International journal of immunopathology and pharmacology · 2016Trial
- Homeopathic Medicines for the Treatment of Acute Otitis Media: a Real-World Cohort Study on Recurrences and Antibiotic Prescriptions Compared to those with Conventional Treatments.Homeopathy : the journal of the Faculty of Homeopathy · 2026Article
- Use of osteopathic manipulation techniques for management of acute otitis media in pediatric patients: a scoping review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Article
- Cultural adaptation of the Pan-Canadian Oncology Symptom triage and remote support practice guide for cancer-related fatigue in China: Integration of traditional Chinese medicine nursing evidence.Asia-Pacific journal of oncology nursing · 2023Article
- Prevention of New Respiratory Episodes in Children with Recurrent Respiratory Infections: An Expert Consensus Statement.Microorganisms · 2020Review
- Upper Respiratory Tract Microbiome and Otitis Media Intertalk: Lessons from the Literature.Journal of clinical medicine · 2020Review
- Inflammation, infection, and allergy of upper airways: new insights from national and real-world studies.Italian journal of pediatrics · 2020Article
- Oral prednisolone for acute otitis media in children: a pilot, pragmatic, randomised, open-label, controlled study (OPAL study).Pilot and feasibility studies · 2020Article
- Translating Recent Microbiome Insights in Otitis Media into Probiotic Strategies.Clinical microbiology reviews · 2019Review
- Immunity-targeted approaches to the management of chronic and recurrent upper respiratory tract disorders in children.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2019Review
- Vitamin D and Otitis Media.Current allergy and asthma reports · 2019Review
- Supervised Nasal Saline Irrigations in Otitis-Prone Children.Frontiers in pediatrics · 2019Article
- Oral prednisolone for acute otitis media in children: protocol of a pilot randomised, open-label, controlled study (OPAL study).Pilot and feasibility studies · 2018Article
- Phenotype Profiling and Allergy in Otitis-Prone Children.Frontiers in pediatrics · 2018Article
- Nasopharyngeal microbiota in infants and changes during viral upper respiratory tract infection and acute otitis media.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Otitis media (OM) has numerous presentations in children. Together with conventional medical therapies aimed to prevent and/or treat OM, a rising number of complementary and alternative medicine (CAM) treatment options can be offered. Since OM is common in children, parents may ask healthcare professionals about possible CAM therapies. Many physicians feel that their knowledge is limited regarding these therapies, and that they desire some information. Therefore, we conducted a literature review of CAM therapies for OM, taking into account that many of these treatments, their validity and efficacy and have not been scientifically demonstrated.We performed a search in MEDLINE (accessed via PubMed) using the following terms: "CAM" in conjunction with "OM" and "children. Retrieved publications regarding treatment of OM in children which included these terms included randomized controlled trials, prospective/retrospective studies, and case studies.The following CAM options for OM treatment in children were considered: acupuncture, homeopathy, herbal medicine/phytotherapy, osteopathy, chiropractic, xylitol, ear candling, vitamin D supplement, and systemic and topical probiotics. We reviewed each treatment and described the level of scientific evidence of the relevant publications.The therapeutic approaches commonly associated with CAM are usually conservative, and do not include drugs or surgery. Currently, CAM is not considered by physicians a potential treatment of OM, as there is limited supporting evidence. Further studies are warranted in order to evaluate the potential value of CAM therapies for OM.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.