ArticleEBioMedicine2016
Research Investments in Global Health: A Systematic Analysis of UK Infectious Disease Research Funding and Global Health Metrics, 1997-2013.
Article in EBioMedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Health-related quality of life due to malaria: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Pooled it
- A Systematic Review of Typhoid Fever Occurrence in Africa.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Pooled it
- Allocation of funding into blast injury-related research and blast traumatic brain injury between 2000 and 2019: analysis of global investments from public and philanthropic funders.BMJ military health · 2023Article
- High-throughput sequencing technologies in the detection of livestock pathogens, diagnosis, and zoonotic surveillance.Computational and structural biotechnology journal · 2022Review
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- Integrated Management of Childhood Illnesses (IMCI): a mixed-methods study on implementation, knowledge and resource availability in Malawi.BMJ paediatrics open · 2021Article
- Participant compensation in global health research: a case study.International health · 2020Article
- The allocation of USdollar;105 billion in global funding from G20 countries for infectious disease research between 2000 and 2017: a content analysis of investments.The Lancet. Global health · 2020Article
- Limited alignment of publicly competitive disease funding with disease burden in Japan.PloS one · 2020Article
- Databases for Research and Development.Emerging infectious diseases · 2019Article
- Priority-setting in public health research funding organisations: an exploratory qualitative study among five high-profile funders.Health research policy and systems · 2018Article
- A systematic analysis of UK cancer research funding by gender of primary investigator.BMJ open · 2018Article
- Hepatitis B virus infection as a neglected tropical disease.PLoS neglected tropical diseases · 2017Article
- Global funding trends for malaria research in sub-Saharan Africa: a systematic analysis.The Lancet. Global health · 2017Article
- Investments in cancer research awarded to UK institutions and the global burden of cancer 2000-2013: a systematic analysis.BMJ open · 2017Article
- Is there enough research output of EU projects available to assess and improve health system performance? An attempt to understand and categorise the output of EU projects conducted between 2002 and 2012.Health research policy and systems · 2017Article
- Community-acquired pneumonia in the United Kingdom: a call to action.Pneumonia (Nathan Qld.) · 2017Article
- The cost of scientific excellence - could it be expensive and out of reach?Croatian medical journal · 2016Article
- Research funding for addressing tobacco-related disease: an analysis of UK investment between 2008 and 2012.BMJ open · 2016Article
- The activity of the Research Investments in Global Health study and ways forward within the global funding and policy landscape.BMC proceedings · 2016Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfectious diseases account for a significant global burden of disease and substantial investment in research and development. This paper presents a systematic assessment of research investments awarded to UK institutions and global health metrics assessing disease burden.
methodsWe systematically sourced research funding data awarded from public and philanthropic organisations between 1997 and 2013. We screened awards for relevance to infection and categorised data by type of science, disease area and specific pathogen. Investments were compared with mortality, disability-adjusted life years (DALYs) and years lived with disability (YLD) across three time points.
findingsBetween 1997-2013, there were 7398 awards with a total investment of £3.7 billion. An increase in research funding across 2011-2013 was observed for most disease areas, with notable exceptions being sexually transmitted infections and sepsis research where funding decreased. Most funding remains for pre-clinical research (£2.2 billion, 59.4%). Relative to global mortality, DALYs and YLDs, acute hepatitis C, leishmaniasis and African trypanosomiasis received comparatively high levels of funding. Pneumonia, shigellosis, pertussis, cholera and syphilis were poorly funded across all health metrics. Tuberculosis (TB) consistently attracts relatively less funding than HIV and malaria.
interpretationMost infections have received increases in research investment, alongside decreases in global burden of disease in 2013. The UK demonstrates research strengths in some neglected tropical diseases such as African trypanosomiasis and leishmaniasis, but syphilis, cholera, shigellosis and pneumonia remain poorly funded relative to their global burden. Acute hepatitis C appears well funded but the figures do not adequately take into account projected future chronic burdens for this condition. These findings can help to inform global policymakers on resource allocation for research investment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.