ReviewFrontiers in cellular and infection microbiology2016
Hemorrhagic Fever with Renal Syndrome: Pathogenesis and Clinical Picture.
Review in Frontiers in cellular and infection microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 129 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
129 citing papers in PubMed, 3 syntheses or guidelines pooled it, 272 citations in OpenAlex.
- A systematic review of ultrasound to predict severe disease in patients with dengue and other viral infections associated with hemorrhagic fevers.PLoS neglected tropical diseases · 2026Pooled it
- Incidence rate of hemorrhagic fever with renal syndrome complicated with acute pancreatitis: a meta-analysis.Frontiers in medicine · 2024Pooled it
- Epidemiological and clinical characteristics of death from hemorrhagic fever with renal syndrome: a meta-analysis.Frontiers in microbiology · 2024Pooled it
- A Systems Vaccinology Approach Reveals the Mechanisms of Immunogenic Responses to Hantavax Vaccination in Humans.Scientific reports · 2019Trial
- Clinical severity and health-seeking behaviors of cases with hemorrhagic fever with renal syndrome: A comparative study across spatial clusters in Jiangxi Province, China.PLoS neglected tropical diseases · 2026Article
- Article
- Omics Approaches in Hantavirus Research: Current Advances, Challenges, and Future Perspectives.Biotech (Basel (Switzerland)) · 2026Review
- Maintenance of Hokkaido virus, a genotype ofJournal of virology · 2026Article
- Hantavirus stability and inactivation.PLoS neglected tropical diseases · 2026Article
- A molecular survey of orthohantaviruses in rodents across the tri-border region of China, Russia, and North Korea.PLoS neglected tropical diseases · 2026Article
- Clinical Value the Neutrophil CD64 Index in Predicting the Severity of Hemorrhagic Fever With Renal Syndrome.Immunity, inflammation and disease · 2026Article
- The role of soluble thrombomodulin (sTM) in risk stratification of hemorrhagic fever with renal syndrome and prognostic assessment.PLoS neglected tropical diseases · 2026Article
- Multiplex PCR and nanopore sequencing reveal the genetic stability of Hantaan virus in Xi'an, China.Archives of virology · 2026Article
- Single and combined use of the platelet-lymphocyte ratio and neutrophil-lymphocyte ratio in hemorrhagic fever with renal syndrome.Frontiers in cellular and infection microbiology · 2026Article
- Admission complete blood count-derived inflammatory indices for risk stratification in hemorrhagic fever with renal syndrome: comparative performance of NLR, PLR, SII, LMR, and the neutrophil-to-red blood cell ratio.Frontiers in immunology · 2026Article
- Epidemiological Investigation and Analysis ofTransboundary and emerging diseases · 2026Article
- t-PA/PAI-1 complex expression correlates with the severity in hantaan virus-induced hemorrhagic fever with renal syndrome.Frontiers in cellular and infection microbiology · 2026Article
- Analysis of factors influencing hemorrhagic fever with renal syndrome and its prediction in Weifang, China from 2013 to 2021.Osong public health and research perspectives · 2025Article
- Laboratory Data Analysis of Hemorrhagic Fever With Renal Syndrome Patients to Predict Disease Severity and Patient Prognosis.Journal of clinical laboratory analysis · 2025Article
- Article
69 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hantaan virus (HTNV) causes hemorrhagic fever with renal syndrome (HFRS), which is a zoonosis endemic in eastern Asia, especially in China. The reservoir host of HTNV is field mouse (Apodemus agraricus). The main manifestation of HFRS, including acute kidney injury, increases vascular permeability, and coagulation abnormalities. In this paper, we review the current knowledge of the pathogenesis of HFRS including virus factor, immunity factor and host genetic factors. Furthermore, the treatment and prevention will be discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.