Evidence map›Paper›PMID 26870683›Full record

ArticleJournal of traditional and complementary medicine2016

Effects of white rice containing enriched gamma-aminobutyric acid on blood pressure.

Mie Nishimura, Shin-Ichi Yoshida, Masafumi Haramoto, Hidenori Mizuno, Tomohiko Fukuda, Hiroyo Kagami-Katsuyama, Aiko Tanaka, Tatsuya Ohkawara, Yuji Sato, Jun Nishihira

Abstract read
In one paragraph

Article in Journal of traditional and complementary medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
  2. Review
  3. Germination and Polishing Reshape Microbial Communities inJournal of agricultural and food chemistry · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. ProbioticCurrent research in food science · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Gamma-aminobutyric acid-salt attenuated high cholesterol/high salt diet induced hypertension in mice.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2021
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mie NishimuraDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu, Hokkaido, Japan.
Shin-Ichi YoshidaHokuren Agricultural Research Institute, Higashi-ku, Sapporo, Japan.
Masafumi HaramotoSatake Co., Ltd., Higashihiroshima, Hiroshima, Japan.
Hidenori MizunoSatake Co., Ltd., Higashihiroshima, Hiroshima, Japan.
Tomohiko FukudaHokuren Agricultural Research Institute, Higashi-ku, Sapporo, Japan.
Hiroyo Kagami-KatsuyamaDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu, Hokkaido, Japan.
Aiko TanakaDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu, Hokkaido, Japan.
Tatsuya OhkawaraDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu, Hokkaido, Japan.
Yuji SatoDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu, Hokkaido, Japan.
Jun NishihiraDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu, Hokkaido, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter with beneficial effects including antihypertension and antistress properties. In this study, we examined the effects of GABA-enriched white rice (GABA rice) on blood pressure (BP) in 39 mildly hypertensive adults in a randomized, double-blind, placebo-controlled study. The participants were divided into a test group (n = 22) who consumed rice with 11.2 mg GABA/100 g of rice and a placebo group (n = 17) who consumed rice with 2.7 mg GABA/100 g of rice. For 8 weeks, the participants took 150 g of either the GABA rice or the placebo rice. Hematological examinations were performed on both groups at 0, 4, and 8 weeks after the start of rice consumption. Home BP was self-measured two times daily, morning and evening, from 1 weeks before to 2 weeks after the intervention. Although the hospital BP and evening BP measurements of the participants showed no significant change, consumption of the GABA rice improved the morning BP compared with the placebo rice after the 1(st) week and during the 6(th) and 8(th) weeks. These results showed the possibility that the GABA rice improves morning hypertension.

Indexed as

gamma-aminobutyric acidgamma-aminobutyric acid-enriched white ricehome blood pressuremorning blood pressurewhite rice

Identifiers

PMID26870683
PMCPMC4738072

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.