ArticleMethodsX2016
Analysis of hair cortisol levels in captive chimpanzees: Effect of various methods on cortisol stability and variability.
Article in MethodsX, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 47 citations in OpenAlex.
- Beyond the Mission: Long-Term Endocrine Dynamics in Search and Rescue Dog-Handler Teams.Animals : an open access journal from MDPI · 2026Article
- Hair cortisol concentrations in clipped and combed hair and associations with characteristics, health status and stress in domestic cats.Scientific reports · 2024Article
- Hair cortisol stability after 5-year storage: Insights from a sample of 17-year-old adolescents.Comprehensive psychoneuroendocrinology · 2024Article
- Hair cortisol of pigs in mixed organic farms: the influence of season, breeding system and sex.Frontiers in veterinary science · 2024Article
- Technical validation and a comparison of two methods to quantify individual levels of glucocorticoids in Alpine marmot hair.MethodsX · 2023Article
- Hair cortisol concentration in finishing pigs on commercial farms: variability between pigs, batches, and farms.Frontiers in veterinary science · 2023Article
- Determination of hair cortisol in horses: comparison of immunoassay vs LC-HRMS/MS.Analytical and bioanalytical chemistry · 2022Article
- Impact of hair type, hair sample weight, external hair exposures, and race on cumulative hair cortisol.Psychoneuroendocrinology · 2022Article
- Are Hair Cortisol Levels of Humans, Cats, and Dogs from the Same Household Correlated?Animals : an open access journal from MDPI · 2022Article
- Hair cortisol concentration reflects the life cycle and management of grey wolves across four European populations.Scientific reports · 2022Article
- The Effect of Body Region on Hair Cortisol Concentration in Common Marmosets (Comparative medicine · 2021Article
- The nonhuman primate neuroimaging and neuroanatomy project.NeuroImage · 2021Review
- Article
- Degradation of Temminck's pangolin (MethodsX · 2021Article
- A review of research in primate sanctuaries.Biology letters · 2020Review
- Article
- Common marmoset (Callithrix jacchus) personality, subjective well-being, hair cortisol level and AVPR1a, OPRM1, and DAT genotypes.Scientific reports · 2018Article
- Quantification of hair cortisol concentration in common marmosets (Callithrix jacchus) and tufted capuchins (Cebus apella).American journal of primatology · 2018Article
- Social relationship and hair cortisol level in captive male chimpanzees (Pan troglodytes).Primates; journal of primatology · 2018Article
- A longitudinal study of hair cortisol concentrations in Macaca nemestrina mothers and infants.American journal of primatology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hair cortisol has been reported to be a useful measure of long-term hypothalamic-pituitary-adrenal (HPA) axis activation in several species. It serves as a practical tool for long-term stress assessment, but it is important to understand the methodological factors that can affects hair cortisol assays to avoid methodological artifacts. To that end, we tested several procedures for measuring cortisol levels in hair collected from captive chimpanzees. The results showed that reproducibility was high, and we found no differences in cortisol levels among the various storage, drying, and sampling methods. However, the fineness of homogenized hair, sample weight, and extraction time affected absolute hair cortisol concentration. Although hair cortisol levels were stable over time, factors that may influence measurement results should be kept constant throughout a study.•We modified and validated a methodology involving enzyme immunoassays to reliably measure the hair cortisol levels of captive chimpanzees.•The results revealed that the fineness of homogenized hair, sample weight, and extraction time caused variations in absolute hair cortisol concentrations in chimpanzees. In contrast, storage, drying, and sampling from similar body parts did not affect the results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.