Evidence map›Paper›PMID 26870326›Full record

ArticleBiomedical reports2016

Efficacy of traditional Chinese medicine in treating cancer.

Jiao Nie, Changlin Zhao, L I Deng, Jia Chen, Bin Yu, Xianlin Wu, Peng Pang, Xiaoyin Chen

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Biomedical reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04843865 (A Systemic Approach to Study the Traditional Chinese Medicine as an Adjuvant Treatment in Breast Cancer Patients), which is not on this map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04843865 narecruitingnot on this mapstarted 2022, after this paper: background citation

A Systemic Approach to Study the Traditional Chinese Medicine as an Adjuvant Treatment in Breast Cancer Patients

TypeinterventionalSponsorUniversiti Tunku Abdul RahmanRan2022 to 2024Enrolled30ConditionsBreast Cancer, Musculoskeletal PainArmsChinese Herbs
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 118 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Mini reviews in medicinal chemistry · 2024
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Active Ingredients from Chinese Medicine for Combination Cancer Therapy.International journal of biological sciences · 2023
    Review
  17. Network Pharmacology Analysis and Experimental Verification on Antiangiogenesis Mechanism ofEvidence-based complementary and alternative medicine : eCAM · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jiao NieDepartment of Traditional Chinese Medicine, Medical College of Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Changlin ZhaoDepartment of Traditional Chinese Medicine, Medical College of Jinan University, Guangzhou, Guangdong 510632, P.R. China; Department of Oncology, Clifford Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong 510632, P.R. China.
L I DengDepartment of Traditional Chinese Medicine, Medical College of Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Jia ChenDepartment of Traditional Chinese Medicine, Medical College of Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Bin YuDepartment of Traditional Chinese Medicine, Medical College of Jinan University, Guangzhou, Guangdong 510632, P.R. China; Clinical Institute, Jining Medical University, Jining, Shandong 272013, P.R. China.
Xianlin WuDepartment of Traditional Chinese Medicine, Medical College of Jinan University, Guangzhou, Guangdong 510632, P.R. China; Department of Pancreatic Disease Center, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Peng PangDepartment of Traditional Chinese Medicine, Medical College of Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Xiaoyin ChenDepartment of Traditional Chinese Medicine, Medical College of Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Jinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The morbidity associated with cancer has rapidly increased in recent years, and in the previous 5 years has had a tendency to be the leading cause of fatality compared with cardiovascular disease. Therefore, effective measures are required with an aim to reduce the incidence. Based on the results of clinical investigation, a multidisciplinary treatment strategy for cancer, which includes radiotherapy, chemotherapy, surgery, targeted therapy and immunotherapy, are prominently used in clinical practice. However, the therapies are insufficient due to multidrug resistance, adverse effects and the presence of the root of the cancer. Therefore, there is a necessity to develop more effective or adjunctive therapies for cancer prevention and treatment. Cancer is now widely recognized as a systemic humoral disease. Similarly, the function of herbal drugs is to modulate the whole body system in a more holistic way. Recently, herbal drugs have been applied to one of the efficient approaches for cancer therapy. Furthermore, there is evidence that various herbal medicines have been proven to be useful and effective in sensitizing the conventional agents against the various factors at the cellular and molecular levels that are associated with the occurrence of cancer and in prolonging survival time, alleviating side effects of chemotherapy and radiotherapy and improving the quality of life in cancer patients.

Indexed as

cancercellular and molecular levelherbal medicinesquality of lifeside effectssurvival time

Identifiers

PMID26870326
PMCPMC4726876
OpenAlexW2158991004

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.