ArticleFrontiers in plant science2016
Genome-Wide Identification and Comparative Analysis of Cytosine-5 DNA Methyltransferase and Demethylase Families in Wild and Cultivated Peanut.
Article in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29 citing papers in PubMed, 72 citations in OpenAlex.
- Genome-Wide Identification and Functional Analysis of DNA Methylation-Related Genes inPlants (Basel, Switzerland) · 2026Article
- Genome-Wide Identification of DNA Methyltransferase and Demethylase inPlants (Basel, Switzerland) · 2025Article
- Characterization and differential expression of DNA methyltransferase and demethylase genes in response to abiotic stress in Isodon rubescens.BMC plant biology · 2025Article
- Transcriptional response of cultivated peanut (Arachis hypogaea L.) roots to salt stress and the role of DNA methylation.Plant cell reports · 2025Article
- Systematic Analysis of DNA Demethylase Gene Families in Foxtail Millet (International journal of molecular sciences · 2024Article
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- Comparative Genomic and Expression Analysis Insight into Evolutionary Characteristics ofInternational journal of molecular sciences · 2022Article
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- Identification and gene expression analysis of cytosine-5 DNA methyltransferase and demethylase genes inFrontiers in plant science · 2022Article
- Identification and Characterization of DNA Demethylase Genes and Their Association With Thermal Stress in Wheat (Frontiers in genetics · 2022Article
- The interplay of DNA methyltransferases and demethylases with tuberization genes in potato (Frontiers in plant science · 2022Article
- Genome-wide identification and transcriptional characterization of DNA methyltransferases conferring temperature-sensitive male sterility in wheat.BMC genomics · 2021Article
- Genome-wide identification and analysis of DNA methyltransferase and demethylase gene families in Dendrobium officinale reveal their potential functions in polysaccharide accumulation.BMC plant biology · 2021Article
- Genome-Wide Identification of Epigenetic Regulators inInternational journal of molecular sciences · 2020Article
- DNA methylation and expression analyses reveal epialleles for the foliar disease resistance genes in peanut (Arachis hypogaea L.).BMC research notes · 2020Article
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- Genome-Wide Identification of DNA Methylases and Demethylases in Kiwifruit (Frontiers in plant science · 2020Article
- Molecular and transcriptional characterization of phosphatidyl ethanolamine-binding proteins in wild peanuts Arachis duranensis and Arachis ipaensis.BMC plant biology · 2019Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA methylation plays important roles in genome protection, regulation of gene expression and is associated with plants development. Plant DNA methylation pattern was mediated by cytosine-5 DNA methyltransferase and demethylase. Although the genomes of AA and BB wild peanuts have been fully sequenced, these two gene families have not been studied. In this study we report the identification and analysis of putative cytosine-5 DNA methyltransferases (C5-MTases) and demethylases in AA and BB wild peanuts. Cytosine-5 DNA methyltransferases in AA and BB wild peanuts could be classified in MET, CMT, and DRM2 groups based on their domain organization. This result was supported by the gene and protein structural characteristics and phylogenetic analysis. We found that some wild peanut DRM2 members didn't contain UBA domain which was different from other plants such as Arabidopsis, maize and soybean. Five DNA demethylase encoding genes were found in AA genome and five in BB genome. The selective pressure analysis showed that wild peanut C5-MTase genes mainly underwent purifying selection but many positive selection sites can be detected. Conversely, DNA demethylase genes mainly underwent positive selection during evolution. Additionally, the expression dynamic of cytosine-5 DNA methyltransferase and demethylase genes in different cultivated peanut tissues were analyzed. Expression result showed that cold, heat or PEG stress could influence the expression level of C5-MTase and DNA demethylase genes in cultivated peanut. These results are useful for better understanding the complexity of these two gene families, and will facilitate epigenetic studies in peanut in the future.
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