ReviewDialogues in clinical neuroscience2015
The effects of drugs on human models of emotional processing: an account of antidepressant drug treatment.
Review in Dialogues in clinical neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Effects of benzodiazepines administration on identification of facial expressions of emotion: a meta-analysis.Psychopharmacology · 2020Pooled it
- Lithium effects on impulsivity and emotional processing.Scientific reports · 2025Trial
- Sex differences in activations to the sight of faces, scenes, body parts and tools in visual and non-visual cortical regions leading to the human hippocampus.Biology of sex differences · 2026Article
- Comparing affective bias modification by first- and second-generation antidepressants in male rats using a translational behavioural task.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Negative bias in encoding and recall memory in depressed patients with inadequate response to antidepressant medication.Psychopharmacology · 2026Article
- Examining memory reconsolidation as a mechanism of nitrous oxide's antidepressant action.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Review
- Emotionally adaptive support: a narrative review of affective computing for mental health.Frontiers in digital health · 2025Review
- How do serotonergic psychedelics treat depression: The potential role of neuroplasticity.World journal of psychiatry · 2021Review
- Cognitive neuropsychological theory of antidepressant action: a modern-day approach to depression and its treatment.Psychopharmacology · 2021Review
- Psychedelic Medicines in Major Depression: Progress and Future Challenges.Advances in experimental medicine and biology · 2021Review
- Precision biomarkers for mood disorders based on brain imaging.BMJ (Clinical research ed.) · 2020Article
- Modeling anxiety in healthy humans: a key intermediate bridge between basic and clinical sciences.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019Review
- Serotonergic hallucinogens and recognition of facial emotion expressions: a systematic review of the literature.Therapeutic advances in psychopharmacology · 2019Review
- Deficits in emotion recognition are associated with depressive symptoms in youth with disruptive mood dysregulation disorder.Depression and anxiety · 2018Article
- Changing the Way We Think About (and With) Antidepressants.Biological psychiatry · 2018Article
- Fluoxetine Administration in Juvenile Monkeys: Implications for Pharmacotherapy in Children.Frontiers in pediatrics · 2018Review
- Further validation of the affective bias test for predicting antidepressant and pro-depressant risk: effects of pharmacological and social manipulations in male and female rats.Psychopharmacology · 2017Article
- Irritability in Youths: A Translational Model.The American journal of psychiatry · 2017Review
- Regulation of emotional response in juvenile monkeys treated with fluoxetine: MAOA interactions.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human models of emotional processing suggest that the direct effect of successful antidepressant drug treatment may be to modify biases in the processing of emotional information. Negative biases in emotional processing are documented in depression, and single or short-term dosing with conventional antidepressant drugs reverses these biases in depressed patients prior to any subjective change in mood. Antidepressant drug treatments also modulate emotional processing in healthy volunteers, which allows the consideration of the psychological effects of these drugs without the confound of changes in mood. As such, human models of emotional processing may prove to be useful for testing the efficacy of novel treatments and for matching treatments to individual patients or subgroups of patients.
Indexed as
Identifiers
26869848PMC4734885W2259267629What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.