ReviewClinical ophthalmology (Auckland, N.Z.)2016
Minimally invasive glaucoma surgery: current status and future prospects.
Review in Clinical ophthalmology (Auckland, N.Z.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03138928 (XEN45 Gel Stent Implantation in Glaucoma Surgery), which is not on this map. Cited by 193 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
XEN45 Gel Stent Implantation in Glaucoma Surgery
Who cites it
193 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Efficacy and safety of goniotomy and gonioscopy-assisted transluminal trabeculotomy for exfoliation glaucoma: a systematic review and single-arm meta-analysis.Frontiers in medicine · 2026Pooled it
- Rising or receding? a decade of bibliometric and altmetric trends in gonioscopy-assisted transluminal trabeculotomy research (2014-2024).International ophthalmology · 2025Pooled it
- Efficacy of XEN gel stent implantation combined with mitomycin C injection in the treatment of open-angle glaucoma: a meta-analysis.International ophthalmology · 2024Pooled it
- Pooled it
- Subconjunctival draining minimally-invasive glaucoma devices for medically uncontrolled glaucoma.The Cochrane database of systematic reviews · 2018Pooled it
- Minimally-invasive glaucoma surgeries (MIGS) for open angle glaucoma: A systematic review and meta-analysis.PloS one · 2017Pooled it
- Biotissue stent for supraciliary outflow in open-angle glaucoma patients: surgical procedure and first clinical results of an aqueous drainage biostent.The British journal of ophthalmology · 2024Trial
- Safety and Efficacy of STREAMLINE Canaloplasty with Phacoemulsification in Hispanic Adults with Open-Angle Glaucoma: 12-Month Outcomes.Clinical ophthalmology (Auckland, N.Z.) · 2024Trial
- Theoretic scientific rationale of double XEN 45 Gel Stent implant in severe glaucomatous ocular hypertension.International ophthalmology · 2023Trial
- Canaloplasty and Trabeculotomy Combined with Phacoemulsification for Glaucoma: 12-Month Results of the GEMINI Study.Clinical ophthalmology (Auckland, N.Z.) · 2022Trial
- A European Study of the Performance and Safety of MINIject in Patients With Medically Uncontrolled Open-angle Glaucoma (STAR-II).Journal of glaucoma · 2020Trial
- Trial
- Outcomes of phacoemulsification combined with ab interno trabeculotomy: stratified by incision extent, glaucoma severity, and baseline number of medications.Eye (London, England) · 2026Article
- Evaluation of iStent® Inject W in mild to moderate primary open-angle glaucoma - Indian data on pseudophakic eyes.Indian journal of ophthalmology · 2026Article
- Comparison of surgical outcomes of suture gonioscopy-assisted transluminal trabeculotomy versus excisional goniotomy with Kahook dual blade at 12 months.Indian journal of ophthalmology · 2026Article
- Should Schlemm Canal-Based MIGS Be Combined with Cataract Surgery in Patients Receiving Topical Glaucoma Therapy? A Cataract Surgeon-Oriented Review.Journal of clinical medicine · 2026Review
- Canaloplasty via an ab-interno approach in primary open-angle glaucoma: Results from a large case series.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Trabecular Meshwork Thickness Measured by Swept-Source AS-OCT as a Predictor of Surgical Outcomes After Trabecular Micro-Bypass Stent Implantation.Journal of clinical medicine · 2026Article
- Minimally invasive glaucoma surgery: Demystifying trabecular meshwork complex and the concept of surgical management of glaucoma.Indian journal of ophthalmology · 2026Article
- The SKIBI study: Comparative early outcomes of five minimally invasive glaucoma surgeries combined with cataract extraction in Indian patients with primary open-angle glaucoma.Indian journal of ophthalmology · 2026Observational
133 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Minimally invasive glaucoma surgery aims to provide a medication-sparing, conjunctival-sparing, ab interno approach to intraocular pressure reduction for patients with mild-to-moderate glaucoma that is safer than traditional incisional glaucoma surgery. The current approaches include: increasing trabecular outflow (Trabectome, iStent, Hydrus stent, gonioscopy-assisted transluminal trabeculotomy, excimer laser trabeculotomy); suprachoroidal shunts (Cypass micro-stent); reducing aqueous production (endocyclophotocoagulation); and subconjunctival filtration (XEN gel stent). The data on each surgical procedure for each of these approaches are reviewed in this article, patient selection pearls learned to date are discussed, and expectations for the future are examined.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.