Evidence map›Paper›PMID 26869750›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2016

The suprachoroidal space: from potential space to a space with potential.

Elad Moisseiev, Anat Loewenstein, Glenn Yiu

Registry-linked trialAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05038072 (Suprachoroidal Triamcinolone Acetonide for the Treatment of Macular Edema Associated With Retinal Vein Occlusion), which is not on this map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05038072 nacompletednot on this mapstarted 2019, after this paper: background citation

Suprachoroidal Triamcinolone Acetonide for the Treatment of Macular Edema Associated With Retinal Vein Occlusion: A Pilot Study

TypeinterventionalSponsorDamascus UniversityRan2019 to 2021Enrolled16ConditionsMacular Edema, Retinal Vein OcclusionArmssuprachoroidal injection of Triamcinolone Acetonide.
3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Technical feasibility of suprachoroidal filler injection using ultrathin needle in animal model.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
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  10. Experimental and mathematical approaches for drug delivery for the treatment of wet age-related macular degeneration.Journal of controlled release : official journal of the Controlled Release Society · 2023
    Review
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elad MoisseievUC Davis Eye Center, University of California Davis, Sacramento, CA, USA; Ophthalmology Department, Tel Aviv Medical Center, Tel Aviv, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Anat LoewensteinOphthalmology Department, Tel Aviv Medical Center, Tel Aviv, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Glenn YiuUC Davis Eye Center, University of California Davis, Sacramento, CA, USA.

Funding

A nanoparticle platform for targeted delivery of therapeutic agents to retinal pigment epithelial or choroidal endothelial cellsK08EY026101 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI YIU, GLENN · 2016 to 2020
$1.0M
NEI NIH HHS K08 EY026101
6 · The paper itself

Abstract

Recent advances have made it possible to image the suprachoroidal space, and the understanding of its clinical applications is currently being greatly expanded. This opinion piece covers the advances in imaging techniques that enable the demonstration of the suprachoroidal space, and its implication in various retinal pathologies. It also reviews its potential uses as a route for drug delivery for the treatment of retinal diseases, and its use in innovative surgical techniques. Current research is leading the way for the suprachoroidal space to be an aspect of retinal disease diagnosis, monitoring, medical treatment, and surgical manipulation.

Indexed as

drug deliveryenhanced depth imagingpotential spacesuprachoroidal space

Identifiers

PMID26869750
PMCPMC4734808

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.