Evidence map›Paper›PMID 26869704›Full record

ArticlePlant physiology2016

The Thioredoxin GbNRX1 Plays a Crucial Role in Homeostasis of Apoplastic Reactive Oxygen Species in Response to Verticillium dahliae Infection in Cotton.

Yuan-Bao Li, Li-Bo Han, Hai-Yun Wang, Jie Zhang, Shu-Tao Sun, De-Qin Feng, Chun-Lin Yang, Yong-Duo Sun, Nai-Qin Zhong, Gui-Xian Xia

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Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 134 citations in OpenAlex.

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  19. Interactions betweenFrontiers in plant science · 2023
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yuan-Bao LiInstitute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., S.-T.S., D.-Q.F., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); State Key Laboratory of Plant Genomics, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); and University of Chinese Academy of Sciences, Beijing 100049, China (Y.-B.L., Y.-D.S.).ORCID 0000-0001-7238-2261
Li-Bo HanInstitute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., S.-T.S., D.-Q.F., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); State Key Laboratory of Plant Genomics, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); and University of Chinese Academy of Sciences, Beijing 100049, China (Y.-B.L., Y.-D.S.).ORCID 0000-0001-7068-8160
Hai-Yun WangInstitute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., S.-T.S., D.-Q.F., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); State Key Laboratory of Plant Genomics, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); and University of Chinese Academy of Sciences, Beijing 100049, China (Y.-B.L., Y.-D.S.).ORCID 0000-0001-9071-4346
Jie ZhangInstitute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., S.-T.S., D.-Q.F., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); State Key Laboratory of Plant Genomics, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); and University of Chinese Academy of Sciences, Beijing 100049, China (Y.-B.L., Y.-D.S.).
Shu-Tao SunInstitute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., S.-T.S., D.-Q.F., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); State Key Laboratory of Plant Genomics, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); and University of Chinese Academy of Sciences, Beijing 100049, China (Y.-B.L., Y.-D.S.).
De-Qin FengInstitute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., S.-T.S., D.-Q.F., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); State Key Laboratory of Plant Genomics, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); and University of Chinese Academy of Sciences, Beijing 100049, China (Y.-B.L., Y.-D.S.).
Chun-Lin YangInstitute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., S.-T.S., D.-Q.F., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); State Key Laboratory of Plant Genomics, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); and University of Chinese Academy of Sciences, Beijing 100049, China (Y.-B.L., Y.-D.S.).
Yong-Duo SunInstitute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., S.-T.S., D.-Q.F., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); State Key Laboratory of Plant Genomics, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); and University of Chinese Academy of Sciences, Beijing 100049, China (Y.-B.L., Y.-D.S.).
Nai-Qin ZhongInstitute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., S.-T.S., D.-Q.F., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); State Key Laboratory of Plant Genomics, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); and University of Chinese Academy of Sciences, Beijing 100049, China (Y.-B.L., Y.-D.S.) xiagx@im.ac.cn nqzhong@im.ac.cn.
Gui-Xian XiaInstitute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., S.-T.S., D.-Q.F., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); State Key Laboratory of Plant Genomics, Beijing 100101, China (Y.-B.L., L.-B.H., H.-Y.W., J.Z., C.-L.Y., Y.-D.S., N.-Q.Z., G.-X.X.); and University of Chinese Academy of Sciences, Beijing 100049, China (Y.-B.L., Y.-D.S.) xiagx@im.ac.cn nqzhong@im.ac.cn.ORCID 0000-0003-4426-9784
Chinese Academy of Sciences · CNState Key Laboratory of Plant Genomics · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Examining the proteins that plants secrete into the apoplast in response to pathogen attack provides crucial information for understanding the molecular mechanisms underlying plant innate immunity. In this study, we analyzed the changes in the root apoplast secretome of the Verticillium wilt-resistant island cotton cv Hai 7124 (Gossypium barbadense) upon infection with Verticillium dahliae Two-dimensional differential gel electrophoresis and matrix-assisted laser desorption/ionization tandem time-of-flight mass spectrometry analysis identified 68 significantly altered spots, corresponding to 49 different proteins. Gene ontology annotation indicated that most of these proteins function in reactive oxygen species (ROS) metabolism and defense response. Of the ROS-related proteins identified, we further characterized a thioredoxin, GbNRX1, which increased in abundance in response to V. dahliae challenge, finding that GbNRX1 functions in apoplastic ROS scavenging after the ROS burst that occurs upon recognition of V. dahliae Silencing of GbNRX1 resulted in defective dissipation of apoplastic ROS, which led to higher ROS accumulation in protoplasts. As a result, the GbNRX1-silenced plants showed reduced wilt resistance, indicating that the initial defense response in the root apoplast requires the antioxidant activity of GbNRX1. Together, our results demonstrate that apoplastic ROS generation and scavenging occur in tandem in response to pathogen attack; also, the rapid balancing of redox to maintain homeostasis after the ROS burst, which involves GbNRX1, is critical for the apoplastic immune response.

Indexed as

HomeostasisDisease ResistanceGene Expression ProfilingGene Expression Regulation, PlantGene SilencingGossypiumOrgan SpecificityPhylogenyPlant DiseasesPlant ProteinsPlant RootsPlant Vascular BundleProteomicsReactive Oxygen SpeciesThioredoxinsVerticilliumPlant ProteinsReactive Oxygen SpeciesThioredoxins

Identifiers

PMID26869704
PMCPMC4825149
OpenAlexW2268018243

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.