Evidence map›Paper›PMID 26869702›Full record

ArticlePlant physiology2016

expVIP: a Customizable RNA-seq Data Analysis and Visualization Platform.

Philippa Borrill, Ricardo Ramirez-Gonzalez, Cristobal Uauy

Abstract read
In one paragraph

Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 250 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
250citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

250 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  11. Characterization and Fine Mapping ofPlants (Basel, Switzerland) · 2026
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190 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Philippa BorrillJohn Innes Centre, Norwich NR4 7UH, United Kingdom (P.B., C.U.); andGenome Analysis Centre, Norwich NR4 7UH, United Kingdom (R.R.-G.).ORCID 0000-0002-7623-8256
Ricardo Ramirez-GonzalezJohn Innes Centre, Norwich NR4 7UH, United Kingdom (P.B., C.U.); andGenome Analysis Centre, Norwich NR4 7UH, United Kingdom (R.R.-G.).ORCID 0000-0001-5745-7085
Cristobal UauyJohn Innes Centre, Norwich NR4 7UH, United Kingdom (P.B., C.U.); andGenome Analysis Centre, Norwich NR4 7UH, United Kingdom (R.R.-G.) cristobal.uauy@jic.ac.uk.ORCID 0000-0002-9814-1770

Funding

Biotechnology and Biological Sciences Research Council BBS/E/J/000C0628
6 · The paper itself

Abstract

The majority of transcriptome sequencing (RNA-seq) expression studies in plants remain underutilized and inaccessible due to the use of disparate transcriptome references and the lack of skills and resources to analyze and visualize these data. We have developed expVIP, an expression visualization and integration platform, which allows easy analysis of RNA-seq data combined with an intuitive and interactive interface. Users can analyze public and user-specified data sets with minimal bioinformatics knowledge using the expVIP virtual machine. This generates a custom Web browser to visualize, sort, and filter the RNA-seq data and provides outputs for differential gene expression analysis. We demonstrate expVIP's suitability for polyploid crops and evaluate its performance across a range of biologically relevant scenarios. To exemplify its use in crop research, we developed a flexible wheat (Triticum aestivum) expression browser (www.wheat-expression.com) that can be expanded with user-generated data in a local virtual machine environment. The open-access expVIP platform will facilitate the analysis of gene expression data from a wide variety of species by enabling the easy integration, visualization, and comparison of RNA-seq data across experiments.

Indexed as

Sequence Analysis, RNASoftwareStatistics as TopicGene Expression ProfilingGene Expression Regulation, PlantGenes, PlantGenetic Association StudiesInternetReference StandardsReproducibility of ResultsSequence Homology, Nucleic AcidStress, PhysiologicalTriticumUser-Computer Interface

Identifiers

PMID26869702
PMCPMC4825114

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.