ArticleStroke2016
Risk Score for Neurological Complications After Endovascular Treatment of Unruptured Intracranial Aneurysms.
Article in Stroke, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Understanding complication rates in elective endovascular aneurysm repair for consideration of same-day discharge.Neuroradiology · 2026Article
- Technique and device specific diffusion-weighted imaging detected ischemic lesions and occlusion outcomes in endovascular treatment of unruptured aneurysms.Acta neurochirurgica · 2026Article
- One-year outcomes of unruptured intracranial aneurysms < 5 mm in a Latin American multicenter cohort of 1,098 patients.Neurosurgical review · 2026Observational
- Endovascular treatment of unruptured intracranial aneurysms at a single center: Outcomes, selection strategy, and transparent communication for patient decision-making.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Predicting neurological complications post clipping surgery in unruptured intracranial aneurysms using the NEURO score: a multi-center retrospective cohort study.Korean journal of anesthesiology · 2025Observational
- Safety and efficacy of short-term tirofiban combined with dual antiplatelet therapy after flow diverter placement for intracranial aneurysms: a multicenter retrospective study and nomogram for thromboembolic event prediction.Frontiers in neurology · 2025Article
- An overview of decision-making in cerebrovascular treatment strategies: Part I - unruptured aneurysms.Brain & spine · 2024Review
- Recognition of Strokes in the ICU: A Narrative Review.Journal of cardiovascular development and disease · 2023Review
- Rupture discrimination of multiple small (< 7 mm) intracranial aneurysms based on machine learning-based cluster analysis.BMC neurology · 2023Article
- A coarse-to-fine cascade deep learning neural network for segmenting cerebral aneurysms in time-of-flight magnetic resonance angiography.Biomedical engineering online · 2022Article
- Prediction and analysis of periprocedural complications associated with endovascular treatment for unruptured intracranial aneurysms using machine learning.Frontiers in neurology · 2022Article
- The Neuroprotective Effect of Thiopental on the Postoperative Neurological Complications in Patients Undergoing Surgical Clipping of Unruptured Intracranial Aneurysm: A Retrospective Analysis.Journal of clinical medicine · 2021Article
- Endovascular Treatment of Small Ruptured Intracranial Aneurysms (<5 mm) : Long-term Clinical and Angiographic Outcomes and Related Predictors.Clinical neuroradiology · 2020Article
- Coil Embolization for Unruptured Intracranial Aneurysms at the Dawn of Stent Era: Results of the Japanese Registry of Neuroendovascular Therapy (JR-NET) 3.Neurologia medico-chirurgica · 2020Article
- Recovery of oculomotor nerve palsy after endovascular treatment of ruptured posterior communicating artery aneurysm.Neuroradiology · 2017Article
- Unruptured intracranial aneurysms: development, rupture and preventive management.Nature reviews. Neurology · 2016Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeProcedure-related neurological complications are common after endovascular treatment of unruptured intracranial aneurysms. We aimed to develop a score to quantify individual patient risk.
methodsWe retrospectively analyzed consecutive patients who underwent endovascular treatment for unruptured intracranial aneurysms between January 2012 and September 2015. After excluding those who lost to follow-up and those with fusiform unruptured intracranial aneurysms, included patients were randomly divided into a derivation group (60%) and a validation group (40%). A neurological complication was defined as any transient or permanent increase in the modified Rankin Scale score after aneurysm embolization. A risk score for neurological complications was derived from multivariable logistic regression analyses in the derivation group and validated in the validation group.
resultsOverall, 1060 patients were included (636 in the derivation group and 424 in the validation group). The incidence of neurological complications was 5.5% (95% confidence interval, 3.8%-7.4%). A 3-point risk score (S-C-C) was derived to predict neurological complications (size [≥10 mm=1], core areas [yes=1], and cerebral ischemic comorbidity [yes=1]). The incidence of neurological complications varied from 2.2% in 0-point patients to 25.0% in 3-point patients. The score demonstrated significant discrimination (C-statistic, 0.714; 95% confidence interval, 0.624-0.804) and calibration (McFadden R(2), 0.102) in the derivation group. Excellent prediction, discrimination, and calibration properties were reproduced in the validation group.
conclusionsOne in 20 patients will develop neurological complications after endovascular treatment of unruptured intracranial aneurysms. The S-C-C score may be useful for predicting these adverse outcomes based on variables in daily practice.
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