ArticleJournal of neuroscience methods2016
Minimally invasive highly precise monitoring of respiratory rhythm in the mouse using an epithelial temperature probe.
Article in Journal of neuroscience methods, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Dexterous single sniffs for ethological active olfaction.Science advances · 2026Article
- Respiratory pauses highlight sleep architecture in mice.Nature communications · 2026Article
- Visualizing and sonifying neurodata (ViSoND) for enhanced observation.bioRxiv : the preprint server for biology · 2026Article
- Vocal repertoire expansion in singing mice by co-opting a conserved midbrain circuit node.Current biology : CB · 2025Article
- Mice navigate scent trails using predictive policies.bioRxiv : the preprint server for biology · 2025Article
- Surgical Implantation of a Telemetry-Based Pressure Sensor in the Internal Jugular Vein to Monitor Respiration Wirelessly.Bio-protocol · 2025Article
- Challenges in inferring breathing rhythms from olfactory bulb local field potentials.Chemical senses · 2025Article
- Oscillations in the prefrontal-hippocampal circuit couple to respiration-related oscillations during all phases of a working memory task.Frontiers in behavioral neuroscience · 2025Article
- A top-down slow breathing circuit that alleviates negative affect in mice.Nature neuroscience · 2024Article
- Keypoint-MoSeq: parsing behavior by linking point tracking to pose dynamics.Nature methods · 2024Article
- Wireless monitoring of respiration with EEG reveals relationships between respiration, behavior, and brain activity in freely moving mice.Journal of neurophysiology · 2024Article
- Brainstem depolarization-induced lethal apnea associated with gain-of-functionProceedings of the National Academy of Sciences of the United States of America · 2024Article
- MousePZT: A simple, reliable, low-cost device for vital sign monitoring and respiratory gating in mice under anesthesia.PloS one · 2024Article
- A brainstem circuit for the expression of defensive facial reactions in rat.Current biology : CB · 2023Article
- Intranasal Pressure Recording for Monitoring Mouse Respiration.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Machine learning-based clustering and classification of mouse behaviors via respiratory patterns.iScience · 2022Article
- Theory of hierarchically organized neuronal oscillator dynamics that mediate rodent rhythmic whisking.Neuron · 2022Article
- Simultaneous recording of breathing and neural activity in awake behaving mice.STAR protocols · 2022Article
- Divergent brainstem opioidergic pathways that coordinate breathing with pain and emotions.Neuron · 2022Article
- Neural basis of opioid-induced respiratory depression and its rescue.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundRespiration is one of the essential rhythms of life. The precise measurement of respiratory behavior is of great importance in studies addressing olfactory sensory processing or the coordination of orofacial movements with respiration. An ideal method of measurement should reliably capture the distinct phases of respiration without interfering with behavior. NEW
methodThis new method involves chronic implantation of a thermistor probe in a previously undescribed hollow space located above the anterior portion of the nasal cavity without penetrating any soft epithelial tissues.
resultsWe demonstrate the reliability and precision of the method in head-fixed and freely moving mice by directly comparing recorded signals with simultaneous measurements of chest movements and plethysmographic measurements of respiration. COMPARISON WITH EXISTING
methodsCurrent methods have drawbacks in that they are either inaccurate or require invasive placement of temperature or pressure sensors into the sensitive nasal cavity, where they interfere with airflow and cause irritation and damage to the nasal epithelium. Furthermore, surgical placement within the posterior nasal cavity adjacent to the nasal epithelium requires extensive recovery time, which is not necessary with the described method.
conclusionsHere, we describe a new method for recording the rhythm of respiration in awake mice with high precision, without damaging or irritating the nasal epithelium. This method will be effective for measurement of respiration during experiments requiring free movement, as well as those involving imaging or electrophysiology.
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