ArticleScientific reports2016
GMOL: An Interactive Tool for 3D Genome Structure Visualization.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Uchimata: a toolkit for visualization of 3D genome structures on the web and in computational notebooks.Bioinformatics (Oxford, England) · 2026Article
- Design Space and Declarative Grammar for 3D Genomic Data Visualization.IEEE transactions on visualization and computer graphics · 2026Article
- Uchimata: a toolkit for visualization of 3D genome structures on the web and in computational notebooks.ArXiv · 2025Article
- ARGV: 3D genome structure exploration using augmented reality.BMC bioinformatics · 2024Article
- 3D models of fungal chromosomes to enhance visual integration of omics data.NAR genomics and bioinformatics · 2023Article
- CSynth: an interactive modelling and visualization tool for 3D chromatin structure.Bioinformatics (Oxford, England) · 2021Article
- Evidence of constraint in the 3D genome for trans-splicing in human cells.Science China. Life sciences · 2020Article
- GenomeFlow: a comprehensive graphical tool for modeling and analyzing 3D genome structure.Bioinformatics (Oxford, England) · 2019Article
- An Overview of Methods for Reconstructing 3-D Chromosome and Genome Structures from Hi-C Data.Biological procedures online · 2019Review
- Computational methods for analyzing and modeling genome structure and organization.Wiley interdisciplinary reviews. Systems biology and medicine · 2019Review
- Developing novel methods to image and visualize 3D genomes.Cell biology and toxicology · 2018Review
- Challenges for visualizing three-dimensional data in genomic browsers.FEBS letters · 2017Review
- Software tools for visualizing Hi-C data.Genome biology · 2017Review
- The second decade of 3C technologies: detailed insights into nuclear organization.Genes & development · 2016Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been shown that genome spatial structures largely affect both genome activity and DNA function. Knowing this, many researchers are currently attempting to accurately model genome structures. Despite these increased efforts there still exists a shortage of tools dedicated to visualizing the genome. Creating a tool that can accurately visualize the genome can aid researchers by highlighting structural relationships that may not be obvious when examining the sequence information alone. Here we present a desktop application, known as GMOL, designed to effectively visualize genome structures so that researchers may better analyze genomic data. GMOL was developed based upon our multi-scale approach that allows a user to scale between six separate levels within the genome. With GMOL, a user can choose any unit at any scale and scale it up or down to visualize its structure and retrieve corresponding genome sequences. Users can also interactively manipulate and measure the whole genome structure and extract static images and machine-readable data files in PDB format from the multi-scale structure. By using GMOL researchers will be able to better understand and analyze genome structure models and the impact their structural relations have on genome activity and DNA function.
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Registered trials
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