Evidence map›Paper›PMID 26868043›Full record

ReviewCurrent opinion in neurobiology2016

Brain structure and dynamics across scales: in search of rules.

Xiao-Jing Wang, Henry Kennedy

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. A complex network perspective on brain disease.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Cellular basis for cortical network aging in primates.bioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Why brain organoids are not conscious yet.Patterns (New York, N.Y.) · 2024
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Xiao-Jing WangCenter for Neural Science, New York University, 4 Washington Place, New York, NY 10003, USA; NYU-ECNU Joint Institute of Brain and Cognitive Science, NYU Shanghai, Shanghai, China. Electronic address: xjwang@nyu.edu.
Henry KennedyStem Cell and Brain Research Institute, INSERM U1208, 69500 Bron, France; Université de Lyon, Université Lyon I, 69003 Lyon, France.

Funding

Recurrent Neual Circuit Basis of Time Integration and Decision MakingR01MH062349 · NIMH · YALE UNIVERSITY · PI WANG, XIAO-JING · 2001 to 2022
$7.2M
NIMH NIH HHS R01 MH062349
6 · The paper itself

Abstract

Louis Henry Sullivan, the father of skyscrapers, famously stated 'Form ever follows function'. In this short review, we will focus on the relationship between form (structure) and function (dynamics) in the brain. We summarize recent advances on the quantification of directed- and weighted-mesoscopic connectivity of mammalian cortex, the exponential distance rule for mesoscopic and microscopic circuit wiring, a spatially embedded random model of inter-areal cortical networks, and a large-scale dynamical circuit model of money's cortex that gives rise to a hierarchy of timescales. These findings demonstrate that inter-areal cortical networks are dense (hence such concepts as 'small-world' need to be refined when applied to the brain), spatially dependent (therefore purely topological approach of graph theory has limited applicability) and heterogeneous (consequently cortical areas cannot be treated as identical 'nodes').

Indexed as

Models, NeurologicalAnimalsBrainHumans

Identifiers

PMID26868043
PMCPMC5029120

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.