Evidence map›Paper›PMID 26868013›Full record

ReviewJournal of bioenergetics and biomembranes2017

Physiological roles of the mitochondrial permeability transition pore.

Nelli Mnatsakanyan, Gisela Beutner, George A Porter, Kambiz N Alavian, Elizabeth A Jonas

Open access · greenAbstract readReview
In one paragraph

Review in Journal of bioenergetics and biomembranes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 111 citations in OpenAlex.

  1. Article
  2. Melatonin May Improve Post-Thaw Sperm Motility inAntioxidants (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Brain development and bioenergetic changes.Neurobiology of disease · 2024
    Review
  11. Tissue-specific differences in CaPhysiological reports · 2024
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Mitochondrial Permeability Transition in Stem Cells, Development, and Disease.Advances in experimental medicine and biology · 2023
    Review
  19. Isolated Mitochondrial Preparations andCurrent neuropharmacology · 2023
    Review
  20. FoliumPharmaceutical biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Nelli MnatsakanyanDepartment Internal Medicine, Section of Endocrinology, Yale University, New Haven, CT, USA.
Gisela BeutnerDepartment of Pediatrics (Cardiology), University of Rochester Medical Center, Rochester, NY, USA.
George A PorterDepartment of Pediatrics (Cardiology), University of Rochester Medical Center, Rochester, NY, USA.
Kambiz N AlavianDivision of Brain Sciences, Department of Medicine, Imperial College London, London, UK.
Elizabeth A JonasDepartment Internal Medicine, Section of Endocrinology, Yale University, New Haven, CT, USA. elizabeth.jonas@yale.edu.
University of Rochester Medical Center · USYale University · USImperial College London · GB

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Mitochondrial Ion Channels in Hypoxic NeuronsR37NS045876 · NINDS · YALE UNIVERSITY · PI Elizabeth Ann Jonas · 2014 to 2026
$4.9M
Mitochondrial ion channels in hypoxic neuronsR01NS045876 · NINDS · YALE UNIVERSITY · PI JONAS, ELIZABETH ANN · 2004 to 2013
$3.3M
Role of DJ1 in mitochondrial biogenergetics and neuronal metabolismR01NS081746 · NINDS · YALE UNIVERSITY · PI JONAS, ELIZABETH ANN · 2014 to 2018
$2.2M
NCATS NIH HHS UL1 TR001863NINDS NIH HHS R01 NS045876NINDS NIH HHS R01 NS081746NINDS NIH HHS R37 NS045876
6 · The paper itself

Abstract

Neurons experience high metabolic demand during such processes as synaptic vesicle recycling, membrane potential maintenance and Ca

Indexed as

Adenosine TriphosphatasesAdenosine TriphosphateAnimalsCell DeathHumansIon ChannelsMitochondrial MembranesMitochondrial Membrane Transport ProteinsMitochondrial Permeability Transition PoreOxidative PhosphorylationAdenosine TriphosphatasesAdenosine TriphosphateIon ChannelsMitochondrial Membrane Transport ProteinsMitochondrial Permeability Transition PoreATP synthaseMitochondriaPermeability transition poreSynaptic plasticitySynaptic transmission

Identifiers

PMID26868013
PMCPMC4981558
OpenAlexW2283318401

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.