Evidence map›Paper›PMID 26867697›Full record

Trial reportAppetite2016

Reduced reward-driven eating accounts for the impact of a mindfulness-based diet and exercise intervention on weight loss: Data from the SHINE randomized controlled trial.

Ashley E Mason, Elissa S Epel, Kirstin Aschbacher, Robert H Lustig, Michael Acree, Jean Kristeller, Michael Cohn, Mary Dallman, Patricia J Moran, Peter Bacchetti and 3 more

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Appetite, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 66 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00960414 nacompletednot on this map

Supporting Health by Integrating Nutrition and Exercise (SHINE)

TypeinterventionalSponsorUniversity of California, San FranciscoRan2009 to 2013Enrolled194ConditionsObesityArmsSHINE
NCT04171713 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Compared Effects of Mindfulness and Compassion-based Programs on Food Behavior of Patients With Weight Regulation After Bariatric Surgery: a Controlled and Randomized Study

TypeinterventionalSponsorCentro Mente Aberta de MindfulnessRan2019 to 2021Enrolled456ConditionsObesityArmsMindfulness-Based Health Promotion + Treatment as usual, Attachment-based compassion therapy + Treatment as usual, Treatment as usual
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Emotional Eating Interventions for Adults Living With Overweight and Obesity: A Systematic Review and Meta-Analysis of Behaviour Change Techniques.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Pooled it
  3. Pooled it
  4. Third-wave cognitive behaviour therapies for weight management: A systematic review and network meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2020
    Pooled it
  5. Determinants of weight loss maintenance: a systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2019
    Pooled it
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  12. Sustainability of Hiking in Combination with Coaching in Cardiorespiratory Fitness and Quality of Life.International journal of environmental research and public health · 2022
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ashley E MasonUCSF Osher Center for Integrative Medicine, Department of Medicine, USA. Electronic address: ashley.mason@ucsf.edu.
Elissa S EpelUCSF Osher Center for Integrative Medicine, Department of Medicine, USA; UCSF Center for Health and Community, Department of Psychiatry, USA.
Kirstin AschbacherThe Institute for Integrative Health, USA; UCSF Center for Health and Community, Department of Psychiatry, USA.
Robert H LustigUCSF Department of Pediatrics, USA.
Michael AcreeUCSF Osher Center for Integrative Medicine, Department of Medicine, USA.
Jean KristellerIndiana State University, Department of Psychology, USA.
Michael CohnUCSF Osher Center for Integrative Medicine, Department of Medicine, USA.
Mary DallmanUCSF Center for Health and Community, Department of Psychiatry, USA.
Patricia J MoranUCSF Osher Center for Integrative Medicine, Department of Medicine, USA.
Peter BacchettiUCSF Department of Epidemiology and Biostatistics, USA.
Barbara LaraiaUC Berkeley School of Public Health, USA.
Frederick M HechtUCSF Osher Center for Integrative Medicine, Department of Medicine, USA.
Jennifer DaubenmierUCSF Osher Center for Integrative Medicine, Department of Medicine, USA. Electronic address: Jennifer.Daubenmier@ucsf.edu.

Funding

Engaging University of California Stakeholders for Biorespository ResearchUL1TR000004 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$78.0M
UC DAVIS CLINICAL AND TRANSLATIONAL SCIENCE CENTER: BPCAUL1RR024146 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2006 to 2011
$27.0M
UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
Metabolic and Immunologic Effects of Meditation - Cell Aging SupplementP01AT005013 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HECHT, FREDERICK M · 2008 to 2012
$6.8M
Training Researchers in Clinical Integrative Medicine (TRIM) - NOSI supplementT32AT003997 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SHELLEY R ADLER, MARIA T CHAO · 2007 to 2026
$6.6M
Novel interventions to reduce stress induced non-homeostatic eatingU01HL097973 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ADLER, NANCY E, EPEL, ELISSA S. · 2009 to 2014
$5.7M
Mentoring and Research in Integrative MedicineK24AT007827 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HECHT, FREDERICK M · 2013 to 2022
$1.8M
Effects of Mind-Body Interventions on Metabolic Syndrome RiskK01AT004199 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DAUBENMIER, JENNIFER JOAN · 2007 to 2011
$626k
NCATS NIH HHS UL1 TR000004NCCIH NIH HHS 1P01AT005013NCCIH NIH HHS K01 AT004199NCCIH NIH HHS K01AT004199NCCIH NIH HHS K24 AT007827NCCIH NIH HHS K24AT007827NCCIH NIH HHS P01 AT005013NCCIH NIH HHS T32 AT003997NCCIH NIH HHS T32AT003997NCRR NIH HHS UL1 RR024146NHLBI NIH HHS U01 HL097973NHLBI NIH HHS U01HL097973NIDDK NIH HHS P30 DK098722
6 · The paper itself

Abstract

Many individuals with obesity report over eating despite intentions to maintain or lose weight. Two barriers to long-term weight loss are reward-driven eating, which is characterized by a lack of control over eating, a preoccupation with food, and a lack of satiety; and psychological stress. Mindfulness training may address these barriers by promoting awareness of hunger and satiety cues, self-regulatory control, and stress reduction. We examined these two barriers as potential mediators of weight loss in the Supporting Health by Integrating Nutrition and Exercise (SHINE) randomized controlled trial, which compared the effects of a 5.5-month diet and exercise intervention with or without mindfulness training on weight loss among adults with obesity. Intention-to-treat multiple mediation models tested whether post-intervention reward-driven eating and psychological stress mediated the impact of intervention arm on weight loss at 12- and 18-months post-baseline among 194 adults with obesity (BMI: 30-45). Mindfulness (relative to control) participants had significant reductions in reward-driven eating at 6 months (post-intervention), which, in turn, predicted weight loss at 12 months. Post-intervention reward-driven eating mediated 47.1% of the total intervention arm effect on weight loss at 12 months [β = -0.06, SE(β) = 0.03, p = .030, 95% CI (-0.12, -0.01)]. This mediated effect was reduced when predicting weight loss at 18 months (p = .396), accounting for 23.0% of the total intervention effect, despite similar weight loss at 12 months. Psychological stress did not mediate the effect of intervention arm on weight loss at 12 or 18 months. In conclusion, reducing reward-driven eating, which can be achieved using a diet and exercise intervention that includes mindfulness training, may promote weight loss (clinicaltrials.gov registration: NCT00960414).

Indexed as

Appetite RegulationDiet, ReducingFeeding BehaviorMindfulnessPatient ComplianceAdultBody Mass IndexCombined Modality TherapyExerciseFemaleGroup ProcessesHumansHyperphagiaMaleMiddle AgedObesityBehavioral interventionMindful eatingObesityReward-driven eatingWeight loss

Identifiers

PMID26867697
PMCPMC4799744

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.