Evidence map›Paper›PMID 26867170›Full record

ArticleCell host & microbe2016

CRISPR-Cas Gatekeeper: Slow on the Uptake but Gets the Job Done.

Rachel J Whitaker, Carin K Vanderpool

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell host & microbe, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rachel J WhitakerDepartment of Microbiology, University of Illinois at Urbana-Champaign. Electronic address: rwhitaker@life.illinois.edu.
Carin K VanderpoolDepartment of Microbiology, University of Illinois at Urbana-Champaign.
University of Illinois Urbana-Champaign · US

Funding

Molecular Determinants of Regulatory Hierarchy for Bacterial Small RNAsR01GM092830 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI VANDERPOOL, CARIN K · 2010 to 2020
$2.8M
NIGMS NIH HHS GM092830
6 · The paper itself

Abstract

Microbial CRISPR-Cas acts as a defense, but also as a gatekeeper controlling the flow of new genes into microbial genomes. In a recent Cell paper, Jiang et al. (2016) uncover the functional importance of transcription-dependent RNA targeting in type III-A CRISPR-Cas antiviral defense and provide insight into the co-evolution of virus-host symbioses.

Indexed as

CRISPR-Cas SystemsRNA StabilityStaphylococcus epidermidisStaphylococcus Phages

Identifiers

PMID26867170
OpenAlexW2264825057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.