ArticleAmerican journal of respiratory and critical care medicine2016
The Prevalence of Latent Tuberculosis Infection in the United States.
Article in American journal of respiratory and critical care medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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Who cites it
62 citing papers in PubMed, 100 citations in OpenAlex.
- Uncovering Household Tuberculosis Infection Testing and Care Patterns Using a Novel Bioinformatics Linkage Strategy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- Assessing the association between elements of health inequalities and the risk of bacterial infection in high-income countries: a systematic scoping review.Access microbiology · 2026Review
- Analysis of factors influencing latent tuberculosis infection screening using QuantiFERON-TB Gold In-Tube in people living with HIV/AIDS.Frontiers in cellular and infection microbiology · 2025Article
- Utility of microbial cell-free DNA sequencing in the diagnosis of mycobacterial infections in a quaternary care center.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Epidemiology of Latent Tuberculosis in Rheumatic Immune-Mediated Inflammatory Diseases-Study of 1117 Patients and Descriptive Literature Review.Journal of clinical medicine · 2024Article
- Abnormal blood pressure among individuals evaluated for tuberculosis infection in a U.S. public health tuberculosis clinic.Epidemiology and infection · 2024Article
- Factors Associated With the Discontinuation of Two Short-Course Tuberculosis Preventive Therapies in Programmatic Settings in the United States.Open forum infectious diseases · 2024Article
- Prevalence estimates of tuberculosis infection in adults in Denmark: a retrospective nationwide register-based cross-sectional study, 2010 to 2018.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024Article
- Patterns of TB transmission in the United States, 2011-2017.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2024Article
- Article
- Indolent infections in patients with hematologic malignancy: A single-center experience screening for tuberculosis and strongyloidiasis prior to cytotoxic therapy in Boston.Leukemia research reports · 2024Article
- Area-Based Sociodemographic Factors Associated with Latent Tuberculosis Infection in a Low-Prevalence Setting.The American journal of tropical medicine and hygiene · 2023Article
- Examining Test Cutoffs to Optimize Diagnosis of Latent Tuberculosis Infection in People Born Outside the United States.Annals of the American Thoracic Society · 2023Article
- The latent tuberculosis infection cascade of care during the COVID-19 pandemic response in a Mid-Sized US city.Journal of clinical tuberculosis and other mycobacterial diseases · 2023Article
- Latent Tuberculosis in India: An Overview.Cureus · 2023Review
- Multicenter Analysis of Attrition from the Pediatric Tuberculosis Infection Care Cascade in Boston.The Journal of pediatrics · 2023Article
- Evaluation of the Latent Tuberculosis Care Cascade Among Public Health Clinics in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Latent Tuberculosis Infection in Haematopoietic Stem Cell Transplant Recipients: A Retrospective Italian Cohort Study in Tor Vergata University Hospital, Rome.International journal of environmental research and public health · 2022Article
- Testing and treatment for latent tuberculosis infection in people living with HIV and substance dependence: a prospective cohort study.BMJ open · 2022Article
- Prevalence of Latent Tuberculosis Infection Among Non-US-Born Persons by Country of Birth-United States, 2012-2017.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
rationaleIndividuals with latent tuberculosis infection (LTBI) represent a reservoir of infection, many of whom will progress to tuberculosis (TB) disease. A central pillar of TB control in the United States is reducing this reservoir through targeted testing and treatment.
objectivesTo estimate the prevalence of LTBI in the United States using the tuberculin skin test (TST) and an IFN-γ release assay.
methodsWe used nationally representative data from the 2011-2012 National Health and Nutrition Examination Survey (n = 6,083 aged ≥6 yr). LTBI was measured by both the TST and QuantiFERON-TB Gold In-Tube test (QFT-GIT). Weighted population, prevalence, and multiple logistic regression were used. MEASUREMENTS AND MAIN
resultsThe estimated prevalence of LTBI in 2011-2012 was 4.4% as measured by the TST and 4.8% by QFT-GIT, corresponding to 12,398,000 and 13,628,000 individuals, respectively. Prevalence declined slightly since 2000 among the U.S. born but remained constant among the foreign born. Earlier birth cohorts consistently had higher prevalence than more recent ones. Higher risk groups included the foreign born, close contact with a case of TB disease, and certain racial/ethnic groups.
conclusionsAfter years of decline, the prevalence of LTBI remained relatively constant between 2000 and 2011. A large reservoir of 12.4 million still exists, with foreign-born persons representing an increasingly larger proportion of this reservoir (73%). Estimates and risk factors for LTBI were generally similar between the TST and QFT-GIT. The updated estimates of LTBI and associated risk groups can help improve targeted testing and treatment in the United States.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.