Evidence map›Paper›PMID 26865901›Full record

ArticleBiomicrofluidics2016

In-situ photopolymerization of monodisperse and discoid oxidized methacrylated alginate microgels in a microfluidic channel.

Shuo Wang, Oju Jeon, Peter G Shankles, Yuan Liu, Eben Alsberg, Scott T Retterer, Bruce P Lee, Chang Kyoung Choi

Abstract read
In one paragraph

Article in Biomicrofluidics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. AnBiomicrofluidics · 2018
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shuo WangDepartment of Mechanical Engineering-Engineering Mechanics, Michigan Technological University , Houghton, Michigan 49931, USA.
Oju JeonDepartment of Biomedical Engineering, Case Western Reserve University , Cleveland, Ohio 44106, USA.
Peter G Shankles
Yuan LiuDepartment of Biomedical Engineering, Michigan Technological University , Houghton, Michigan 49931, USA.
Eben Alsberg
Scott T Retterer
Bruce P LeeDepartment of Biomedical Engineering, Michigan Technological University , Houghton, Michigan 49931, USA.ORCID 0000-0002-6529-0032
Chang Kyoung ChoiDepartment of Mechanical Engineering-Engineering Mechanics, Michigan Technological University , Houghton, Michigan 49931, USA.

Funding

TRAINING PROGRAM IN MUSCULOSKELETAL RESEARCHT32AR007505 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI TRIOLO, RONALD J · 1986 to 2023
$6.3M
High-Throughput Microenvironment Regulation for ChondrogenesisR01AR066193 · NIAMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ALSBERG, EBEN, KHADEMHOSSEINI, ALI · 2015 to 2020
$2.1M
Driving Tissue Formation by Inductive Stem Cell Sheet TechnologyR01AR063194 · NIAMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ALSBERG, EBEN · 2012 to 2016
$1.7M
Biomimetic Tissue Adhesive with Mechanically Tough Hydrogel SupportR15GM104846 · NIGMS · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI LEE, BRUCE P · 2013 to 2016
$757k
NIAMS NIH HHS R01 AR063194NIAMS NIH HHS R01 AR066193NIAMS NIH HHS T32 AR007505NIGMS NIH HHS R15 GM104846
6 · The paper itself

Abstract

We present a simple microfluidic technique to in-situ photopolymerize (by 365 nm ultraviolet) monodisperse oxidized methacrylated alginate (OMA) microgels using a photoinitiator (VA-086). By this technique, we generated monodisperse spherical OMA beads and discoid non-spherical beads with better shape consistency than ionic crosslinking methods do. We found that a high monomer concentration (8 w/v %), a high photoinitiator concentration (1.5 w/v %), and absence of oxygen are critical factors to cure OMA microgels. This photopolymerizing method is an alternative to current methods to form alginate microgels and is a simpler approach to generate non-spherical alginate microgels.

Identifiers

PMID26865901
PMCPMC4744231

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.