ArticleJournal of epidemiology and community health2016
Are adolescent orphans more likely to be HIV-positive? A pooled data analyses across 19 countries in sub-Saharan Africa.
Article in Journal of epidemiology and community health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- What do we know about children living with HIV-infected or AIDS-ill adults in Sub-Saharan Africa? A systematic review of the literature.AIDS care · 2016Pooled it
- School Support as Structural HIV Prevention for Adolescent Orphans in Western Kenya.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2018Trial
- Effects of HIV and Adverse Childhood Experiences on Neurocognition.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- Determinants of Educational Institution Enrolment Among Orphaned and Vulnerable Children in Namibia: A Multi-Year Analysis 2018-2024.Child: care, health and development · 2025Article
- Orphanhood vulnerabilities for violence and HIV by education, sex, and orphan type among 18-24-year-old youth: findings from the 2018 Lesotho violence against children and youth survey.Psychology, health & medicine · 2024Article
- Article
- A Challenging Knowledge Gap: Estimating Modes of HIV Acquisition Among Adolescents Entering HIV Care During Adolescence.Global pediatric health · 2022Article
- Rates and Determinants of Retention on ART Among Orphans and Vulnerable Children Living With HIV in Tanzania.Frontiers in public health · 2022Article
- Estimating the burden of pediatric HIV in an 'A' category district in India: an epidemiological study.BMC pediatrics · 2021Article
- HIV care coverage among HIV-positive adolescent girls and young women in South Africa: Results from the HERStory Study.South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde · 2021Article
- Poor linkage to care for HIV-positive OVC with disabled caregivers: a longitudinal study in Tanzania.BMC public health · 2021Article
- Article
- Impact evaluation of scripted lesson plans for HIV-related content in a life orientation curriculum: results from two provinces in South Africa.BMC public health · 2020Article
- Understanding the association between caregiver sex and HIV infection among orphans and vulnerable children in Tanzania: learning from the USAID Kizazi Kipya project.BMC health services research · 2020Article
- Article
- Positive and Healthy Living Program Manual Development for Young People Living With HIV at the Comprehensive Care Center at the Kenyatta National Hospital: An Open Pilot Implementation Trial.Frontiers in psychiatry · 2020Article
- Strategies for Identifying and Linking HIV-Infected Infants, Children, and Adolescents to HIV Treatment Services in Resource Limited Settings.Journal of acquired immune deficiency syndromes (1999) · 2018Article
- Why Are Orphaned Adolescents More Likely to Be HIV Positive? Distinguishing Between Maternal and Sexual HIV Transmission Using 17 Nationally Representative Data Sets in Africa.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
backgroundDespite extensive resources and numerous programmes directed towards orphans in sub-Saharan Africa, evidence of their disadvantage is surprisingly limited. While initial research suggests that orphans are at greater risk of being HIV-positive, the evidence is limited in geographic scope.
methodsTo rigorously test disparities in HIV prevalence related to orphanhood and parental HIV status in sub-Saharan Africa, we used Demographic and Health Survey data from 19 countries in sub-Saharan Africa. We conducted pooled multilevel logistic regression on adolescents aged 15-17 years with HIV test results (N=22 837 girls and 20 452 boys).
resultsRegardless of their gender, orphans who lost their mother, lost both parents or had an HIV-infected mother were two to three times more likely to test positive for HIV infection (ORs 1.87-3.17). The loss of a father was also associated with HIV infection risk for females, but of slightly lower magnitude (OR 1.63).
conclusionsTo better inform interventions, future research is needed to quantify the relative contribution of perinatally-acquired and sexually-acquired infections, and to investigate the specific mechanisms that may account for disparities in the latter. In the meantime, programmes serving HIV-infect adults as well as those serving orphaned and vulnerable children should invest in family-based HIV testing in order to identify adolescents in need of treatment.
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