Evidence map›Paper›PMID 26865217›Full record

ArticleScientific reports2016

Genomic study of the Ket: a Paleo-Eskimo-related ethnic group with significant ancient North Eurasian ancestry.

Pavel Flegontov, Piya Changmai, Anastassiya Zidkova, Maria D Logacheva, N Ezgi Altınışık, Olga Flegontova, Mikhail S Gelfand, Evgeny S Gerasimov, Ekaterina E Khrameeva, Olga P Konovalova and 8 more

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  15. Bioinformatics research at BGRS-2018.BMC bioinformatics · 2019
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  18. Dispersals of the Siberian Y-chromosome haplogroup Q in Eurasia.Molecular genetics and genomics : MGG · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Pavel FlegontovDepartment of Biology and Ecology, Faculty of Science, University of Ostrava, Ostrava, Czech Republic.
Piya ChangmaiDepartment of Biology and Ecology, Faculty of Science, University of Ostrava, Ostrava, Czech Republic.
Anastassiya ZidkovaDepartment of Biology and Ecology, Faculty of Science, University of Ostrava, Ostrava, Czech Republic.
Maria D LogachevaA.A. Kharkevich Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, Russia.
N Ezgi AltınışıkDepartment of Biology and Ecology, Faculty of Science, University of Ostrava, Ostrava, Czech Republic.
Olga FlegontovaInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budĕjovice, Czech Republic.
Mikhail S GelfandA.A. Kharkevich Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, Russia.
Evgeny S GerasimovA.A. Kharkevich Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, Russia.
Ekaterina E KhrameevaA.A. Kharkevich Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, Russia.
Olga P KonovalovaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Tatiana NeretinaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Yuri V NikolskyBiomedical Cluster, Skolkovo Foundation, Skolkovo, Russia.
George StarostinRussian State University for the Humanities, Moscow, Russia.
Vita V StepanovaA.A. Kharkevich Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, Russia.
Igor V TravinskyRetired, Moscow, Russia.
Martin TřískaChildren's Hospital Los Angeles, Los Angeles, CA, USA.
Petr TřískaInstituto de Patologia e Imunologia Molecular da Universidade do Porto (IPATIMUP), Porto, Portugal.
Tatiana V TatarinovaA.A. Kharkevich Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, Russia.

Funding

Populaton Pharmacokinetic Modeling and Optimal ControlR01GM068968 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI NEELY, MICHAEL N. · 2003 to 2015
$3.9M
Mechanisms of Hypothermic Neuroprotection in NeonatesR01HD070996 · NICHD · JOHNS HOPKINS UNIVERSITY · PI NORTHINGTON, FRANCES J · 2012 to 2016
$1.7M
NICHD NIH HHS HD070996NICHD NIH HHS R01 HD070996NIGMS NIH HHS GM068968NIGMS NIH HHS R01 GM068968
6 · The paper itself

Abstract

The Kets, an ethnic group in the Yenisei River basin, Russia, are considered the last nomadic hunter-gatherers of Siberia, and Ket language has no transparent affiliation with any language family. We investigated connections between the Kets and Siberian and North American populations, with emphasis on the Mal'ta and Paleo-Eskimo ancient genomes, using original data from 46 unrelated samples of Kets and 42 samples of their neighboring ethnic groups (Uralic-speaking Nganasans, Enets, and Selkups). We genotyped over 130,000 autosomal SNPs, identified mitochondrial and Y-chromosomal haplogroups, and performed high-coverage genome sequencing of two Ket individuals. We established that Nganasans, Kets, Selkups, and Yukaghirs form a cluster of populations most closely related to Paleo-Eskimos in Siberia (not considering indigenous populations of Chukotka and Kamchatka). Kets are closely related to modern Selkups and to some Bronze and Iron Age populations of the Altai region, with all these groups sharing a high degree of Mal'ta ancestry. Implications of these findings for the linguistic hypothesis uniting Ket and Na-Dene languages into a language macrofamily are discussed.

Indexed as

Genome, HumanPhylogenyPolymorphism, Single NucleotideChromosomes, Human, YDNA, MitochondrialEthnicityGenetic VariationHaplotypesHuman MigrationHumansInuitLanguagePhylogeographySiberiaDNA, Mitochondrial

Identifiers

PMID26865217
PMCPMC4750364

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.