Trial reportAmerican journal of human biology : the official journal of the Human Biology Council2016
C-reactive protein increases with gestational age during pregnancy among Chinese women.
Trial report in American journal of human biology : the official journal of the Human Biology Council, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Low-grade inflammation from prenatal period to age 6-8 years in a Vitamin D trial.Pediatric research · 2024Trial
- Maternal and offspring genome-wide association study of C-reactive protein reveals limited polygenic association with gestational diabetes mellitus.BMC genomics · 2026Article
- Nyctalopia during pregnancy due to vitamin A deficiency after bariatric sleeve gastrectomy: A case report.Clinical case reports · 2024Article
- Impact of Disease Activity and Inflammatory Bowel Disease Subtype on Quality of Life in Preconception and Pregnant Patients.Digestive diseases and sciences · 2023Article
- Maternal inflammatory, lipid and metabolic markers and associations with birth and breastfeeding outcomes.Frontiers in nutrition · 2023Article
- Markers of inflammation in obese pregnant women: Adenosine deaminase and high sensitive C - reactive protein.European journal of obstetrics & gynecology and reproductive biology: X · 2022Article
- Iron Deficiency in the United States: Limitations in Guidelines, Data, and Monitoring of Disparities.American journal of public health · 2022Article
- Use of the Electronic Health Record to Assess Prevalence of Anemia and Iron Deficiency in Pregnancy.The Journal of nutrition · 2021Article
- Article
- C-reactive protein predicts complications in community-associated S. aureus bacteraemia: a cohort study.BMC infectious diseases · 2021Article
- Association of Dietary Inflammatory Index with Serum IL-6, IL-10, and CRP Concentration during Pregnancy.Nutrients · 2020Article
- Association between the Inflammatory Potential of Diet and Stress among Female College Students.Nutrients · 2020Article
- Immune function during pregnancy varies between ecologically distinct populations.Evolution, medicine, and public health · 2020Article
- Vitamin A and Pregnancy: A Narrative Review.Nutrients · 2019Review
- Article
- Biomarkers of Nutrition for Development (BOND)-Iron Review.The Journal of nutrition · 2018Review
- Correlates of early pregnancy serum brain-derived neurotrophic factor in a Peruvian population.Archives of women's mental health · 2017Article
- Factors associated with inflammation in preschool children and women of reproductive age: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project.The American journal of clinical nutrition · 2017Review
- Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
objectiveTo examine the concentration of C-reactive protein (CRP) in relation to gestational weeks during pregnancy among Chinese women.
methodsFrom a randomized control trial of prenatal supplementation with folic acid, iron-folic acid, and multiple micronutrients in China, we examined 834 pregnant women with CRP measured initially between 5 and 20 weeks and at follow-up between 28 and 32 weeks gestation. We calculated and plotted CRP geometric means by gestational weeks. The same analysis was repeated for women who had normal pregnancies (624 women) by excluding women with stillbirth, preterm, small for gestational age, body mass index <18.5 kg/m(2) or >30 kg/m(2) at enrollment, and hypertension or anemia during pregnancy.
resultsWe observed a significant positive trend between log-transformed CRP and gestational age from 5 to 20 weeks and from 28 to 32 weeks both in the full sample and in the subset of women who had normal pregnancies. CRP geometric mean was 0.81 mg/l at 5-7 weeks of gestation, 2.85 mg/l at 19-20 weeks of gestation, and 3.89 mg/l at 32 weeks of gestation. A similar increasing trend in the CRP median or percentage of elevated CRP were also observed.
conclusionWe concluded that CRP increased with gestational age among healthy Chinese women who delivered healthy infants. Am. J. Hum. Biol. 28:574-579, 2016. © 2016 Wiley Periodicals, Inc.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.