ReviewJournal of neurophysiology2016
Neuronal responses to tactile stimuli and tactile sensations evoked by microstimulation in the human thalamic principal somatic sensory nucleus (ventral caudal).
Review in Journal of neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Neuroscience of human ventral lateral thalamic nucleus related to movement and movement disorders.Journal of neurophysiology · 2025Review
- Identification of Brain Activation Areas in Response to Active Tactile Stimulation by Gripping a Stress Ball.Brain sciences · 2025Article
- Neuroscience of the human thalamus related to acute pain and chronic "thalamic" pain.Journal of neurophysiology · 2024Review
- Clinical Applications and Future Translation of Somatosensory Neuroprostheses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Functional representation of trigeminal nociceptive input in the human periaqueductal gray.Science advances · 2024Article
- Somatotopic organization of the ventral nuclear group of the dorsal thalamus: deep brain stimulation for neuropathic pain reveals new insights into the facial homunculus.Brain structure & function · 2024Article
- Restoration of sensory information via bionic hands.Nature biomedical engineering · 2023Review
- Fluctuations in Arousal Correlate with Neural Activity in the Human Thalamus.Cerebral cortex communications · 2021Article
- Striatal and Thalamic Auditory Response During Deep Brain Stimulation for Essential Tremor: Implications for Psychosis.Neuromodulation : journal of the International Neuromodulation Society · 2020Article
- Overnight Caloric Restriction Prior to Cardiac Arrest and Resuscitation Leads to Improved Survival and Neurological Outcome in a Rodent Model.Frontiers in neuroscience · 2020Article
- Reorganization of Higher-Order Somatosensory Cortex After Sensory Loss from Hand in Squirrel Monkeys.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Human Thalamic Somatosensory Nucleus (Ventral Caudal, Vc) as a Locus for Stimulation by INPUTS from Tactile, Noxious and Thermal Sensors on an Active Prosthesis.Sensors (Basel, Switzerland) · 2017Review
- Distinct perceptive pathways selected with tonic and bursting patterns of thalamic stimulation.Brain stimulationArticle
- Sensory percepts induced by microwire array and DBS microstimulation in human sensory thalamus.Brain stimulationArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
The normal organization and plasticity of the cutaneous core of the thalamic principal somatosensory nucleus (ventral caudal, Vc) have been studied by single-neuron recordings and microstimulation in patients undergoing awake stereotactic operations for essential tremor (ET) without apparent somatic sensory abnormality and in patients with dystonia or chronic pain secondary to major nervous system injury. In patients with ET, most Vc neurons responded to one of the four stimuli, each of which optimally activates one mechanoreceptor type. Sensations evoked by microstimulation were similar to those evoked by the optimal stimulus only among rapidly adapting neurons. In patients with ET, Vc was highly segmented somatotopically, and vibration, movement, pressure, and sharp sensations were usually evoked by microstimulation at separate sites in Vc. In patients with conditions including spinal cord transection, amputation, or dystonia, RFs were mismatched with projected fields more commonly than in patients with ET. The representation of the border of the anesthetic area (e.g., stump) or of the dystonic limb was much larger than that of the same part of the body in patients with ET. This review describes the organization and reorganization of human Vc neuronal activity in nervous system injury and dystonia and then proposes basic mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.