Evidence map›Paper›PMID 26864745›Full record

ArticleCurrent treatment options in gastroenterology2016

Treat to Target in Inflammatory Bowel Disease.

Peter Bossuyt, Séverine Vermeire

Abstract read
PubMed Publisher
In one paragraph

Article in Current treatment options in gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Radioimmune Imaging of αPharmaceutics · 2023
    Article
  2. Article
  3. An assessment of symptom burden in inflammatory bowel diseases to develop a patient preference-weighted symptom score.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Managing IBD Therapies in Pregnancy.Current treatment options in gastroenterology · 2017
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Peter BossuytDepartment of Gastroenterology, University Hospitals Leuven, KULeuven-University of Leuven, Herestraat 49, 3000, Leuven, Belgium.
Séverine VermeireDepartment of Gastroenterology, University Hospitals Leuven, KULeuven-University of Leuven, Herestraat 49, 3000, Leuven, Belgium. Severine.Vermeire@uzleuven.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

opinion statementWith the expanding armamentarium in IBD the current treatment targets can be reached. By optimally using our drugs we can avoid long-term complications in IBD. For this the therapeutic strategy has to be changed from a clinically driven approach to a target-driven strategy. Currently mucosal healing, normalization of biomarkers, histological healing, and healing on abdominal imaging are proposed targets. Correct phenotyping of the patient before initiation of therapy is mandatory. Once treatment is initiated a continuous re-evaluation with consequent adaptation of the treatment when goals are not (yet) reached is needed. Both escalation and de-escalation should be considered. Drug levels can be used as a guidance to reach these targets.

Indexed as

BiomarkersHistological healingIBDMREMucosal healingTreat to target

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.