Evidence map›Paper›PMID 26864723›Full record

ArticleScientific reports2016

Atlas Toolkit: Fast registration of 3D morphological datasets in the absence of landmarks.

Timothy Grocott, Paul Thomas, Andrea E Münsterberg

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. TheDevelopment (Cambridge, England) · 2020
    Article
  2. Article
  3. The Early Stages of Heart Development: Insights from Chicken Embryos.Journal of cardiovascular development and disease · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Timothy GrocottSchool of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, U.K.
Paul ThomasSchool of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, U.K.
Andrea E MünsterbergSchool of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, U.K.

Funding

Biotechnology and Biological Sciences Research Council BB/K003437
6 · The paper itself

Abstract

Image registration is a gateway technology for Developmental Systems Biology, enabling computational analysis of related datasets within a shared coordinate system. Many registration tools rely on landmarks to ensure that datasets are correctly aligned; yet suitable landmarks are not present in many datasets. Atlas Toolkit is a Fiji/ImageJ plugin collection offering elastic group-wise registration of 3D morphological datasets, guided by segmentation of the interesting morphology. We demonstrate the method by combinatorial mapping of cell signalling events in the developing eyes of chick embryos, and use the integrated datasets to predictively enumerate Gene Regulatory Network states.

Indexed as

Gene Expression Regulation, DevelopmentalGene Regulatory NetworksAnimalsAtlases as TopicAvian Proteinsbeta CateninChick EmbryoDatasets as TopicExtracellular Signal-Regulated MAP KinasesEyeFluorescent Antibody TechniqueImage Processing, Computer-AssistedImaging, Three-DimensionalOrganogenesisPAX6 Transcription FactorPhosphoproteinsAvian Proteinsbeta CateninExtracellular Signal-Regulated MAP KinasesPAX6 Transcription FactorPhosphoproteinsSmad Proteins

Identifiers

PMID26864723
PMCPMC4749973

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.