Evidence map›Paper›PMID 26864370›Full record

Trial reportThe American journal of clinical nutrition2016

Dietary energy requirements in relatively healthy maintenance hemodialysis patients estimated from long-term metabolic studies.

Anuja Shah, Rachelle Bross, Bryan B Shapiro, Gillian Morrison, Joel D Kopple

2 registry-linked trialsOpen access · bronzeAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of clinical nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02194114 nacompletednot on this map

Dietary Protein Intake and Its Effect on Nitrogen Balance in Maintenance Hemodialysis (MHD) Patients

TypeinterventionalSponsorLundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterRan2004 to 2008Enrolled13ConditionsChronic Renal Failure, End-Stage Renal DiseaseArmsProtein Diet
NCT05439174 unknown statusnot on this mapstarted 2022, after this paper: background citation

Impact of Intradialytic Parenteral Nutrition on Nutrition Markers in Patients Receiving In-Center Hemodialysis

TypeobservationalSponsorPatient Care AmericaRan2022 to 2023Enrolled1,200ConditionsEnd-stage Renal Disease, Malnutrition, ProteinArmsIntradialytic Parenteral Nutrition
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Deconstructing Disease-Related Malnutrition: A New Assessment Framework for Clinical Practice.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2023
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Observational
  8. Observational
  9. [An assessment of nutritional status in children on maintenance hemodialysis due to stage 5 chronic kidney disease].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Anuja ShahDivision of Nephrology and Hypertension, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA; David Geffen School of Medicine at UCLA, Los Angeles, CA;
Rachelle BrossUCLA Clinical and Translational Science Institute at the Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Los Angeles, CA;
Bryan B ShapiroMedical School for International Health at Ben-Gurion University, Be'er Sheva, Israel; and.
Gillian MorrisonUCLA Clinical and Translational Science Institute at the Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Los Angeles, CA;
Joel D KoppleDivision of Nephrology and Hypertension, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA; David Geffen School of Medicine at UCLA, Los Angeles, CA; UCLA Fielding School of Public Health, Los Angeles, CA jkopple@labiomed.org.
The Lundquist Institute · USUniversity of California, Los Angeles · USBen-Gurion University of the Negev · IL

Funding

ZONA-FREE HAMSTER OVA ASSAY AS AN INDICATOR OF MALE FERTILITYM01RR000425 · NCRR · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI WANG, CHRISTINA C. · 1985 to 2011
$74.2M
Dietary Protein Requirements in Hemodialysis PatientsR01DK061389 · NIDDK · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI KOPPLE, JOEL DAVID · 2003 to 2007
$1.4M
NCRR NIH HHS 5M01RR000425-36/37NIDDK NIH HHS 5R01DK061389-03/04
6 · The paper itself

Abstract

backgroundStudies that examined dietary energy requirements (DERs) of patients undergoing maintenance hemodialysis (MHD) have shown mixed results. Many studies reported normal DERs, but some described increased energy needs. DERs in MHD patients have been estimated primarily from indirect calorimetry and from nitrogen balance studies. The present study measured DERs in MHD patients on the basis of their dietary energy intake and changes in body composition.

objectiveThis study assessed DERs in MHD patients who received a constant energy intake while changes in their body composition were measured.

designSeven male and 6 female sedentary, clinically stable MHD patients received a constant mean (±SD) energy intake for 92.2 ± 7.9 d while residing in a metabolic research ward. Changes in fat and fat-free mass, measured by dual-energy X-ray absorptiometry, were converted to calorie equivalents and added to energy intake to calculate energy requirements.

resultsThe average DER was 31 ± 3 kcal · kg(-1) · d(-1) calculated from energy intake and change in fat and fat-free calories, which was 28 ± 197 kcal/d over the 92 d of the study. DERs of MHD patients correlated strongly with their body weight (r = 0.81, P = 0.002) and less closely with their measured resting energy expenditure expressed as kcal/d (r = 0.69, P = 0.01). Although the average observed DER in MHD patients was similar to published estimated values for normal sedentary individuals of similar age and sex, there was wide variability in DER among individual patients (range: 26-36 kcal · kg(-1) · d(-1)).

conclusionsAverage DERs of sedentary, clinically stable patients receiving MHD are similar to those of sedentary normal individuals. Our data do not support the theory that MHD patients have increased DERs. Due to the high variability in DERs, careful monitoring of the nutritional status of individual MHD patients is essential. This trial was registered at clinicaltrials.gov as NCT02194114.

Indexed as

Energy IntakeEnergy MetabolismNutritional RequirementsNutritional StatusRenal DialysisSedentary BehaviorAdultAgedBasal MetabolismBody CompositionBody WeightFemaleHumansKidney Failure, ChronicLongitudinal StudiesMalebody compositionchronic kidney diseasechronic kidney failuredietary energy needsrenal nutrition

Identifiers

PMID26864370
PMCPMC4763489
OpenAlexW2272220351

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.