ArticleEuropean journal of nutrition2017
The effect of hypohydration on endothelial function in young healthy adults.
Article in European journal of nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of hypohydration and fluid balance in athletes' cognitive performance: a systematic review.African health sciences · 2022Pooled it
- The Effect of Acute Dehydration upon Muscle Strength Indices at Elite Karate Athletes: A Randomized Crossover Study.Nutrients · 2025Trial
- Impact of supervised exercise on skeletal muscle blood flow and vascular function measured with MRI in patients with peripheral artery disease.American journal of physiology. Heart and circulatory physiology · 2022Trial
- Short-term water deprivation does not increase blood pressure variability or impair neurovascular function in healthy young adults.American journal of physiology. Regulatory, integrative and comparative physiology · 2020Trial
- Is mild dehydration a risk for progression of childhood chronic kidney disease?Pediatric nephrology (Berlin, Germany) · 2024Review
- Hydration Considerations to Improve the Physical Performance and Health of Firefighters.Journal of functional morphology and kinesiology · 2024Review
- Article
- Assessment of Hydration Status and Blood Pressure in a Tertiary Care Hospital at Al-Khobar.Cureus · 2022Article
- Dehydration Status Aggravates Early Renal Impairment in Children: A Longitudinal Study.Nutrients · 2022Article
- Assessing the impact of aging and blood pressure on dermal microvasculature by reactive hyperemia optical coherence tomography angiography.Scientific reports · 2021Observational
- "Case series: ischemic stroke associated with dehydration and arteriosclerosis in individuals with severe anorexia nervosa".Journal of eating disorders · 2021Article
- Assessment of macrovascular and microvascular function in aging males.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Article
- Hydration Status and Cardiovascular Function.Nutrients · 2019Review
- Water deprivation does not augment sympathetic or pressor responses to sciatic afferent nerve stimulation in rats or to static exercise in humans.Journal of applied physiology (Bethesda, Md. : 1985) · 2019Article
- Pre-Practice Hydration Status in Soccer (Football) Players in a Cool Environment.Medicina (Kaunas, Lithuania) · 2018Article
- Free-living, continuous hypo-hydration, and cardiovascular response to exercise in a heated environment.Physiological reports · 2018Article
- Fluid consumption pattern and hydration among 8-14 years-old children.European journal of clinical nutrition · 2018Article
- Influence of sex, menstrual cycle, and oral contraceptives on cerebrovascular resistance and cardiorespiratory function during Valsalva or standing.Journal of applied physiology (Bethesda, Md. : 1985) · 2017Article
- Reply to the letter to the editor.European journal of nutrition · 2016Article
- The effect of hypohydration on endothelial function in healthy adults.European journal of nutrition · 2016Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHypohydration has been suggested as a predisposing factor for several pathologies including cardiovascular diseases (CVD). While CVD are the leading cause of death worldwide, no study has investigated whether acute hypohydration affects endothelial function and cardiovascular function.
methodsTen young, healthy males participated in this crossover study (age: 24.3 ± 2.3 year; weight: 80.8 ± 5.3 kg; BMI: 24.3 ± 0.4 kg m
resultsHypohydration by -1.9 ± 0.1 % of body mass resulted in decreased plasma volume by -3.5 ± 1.8 % and increased plasma osmolality by 9 ± 2 mmol kg
conclusionThe data suggested that a small degree of hypohydration induced by moderate exercise and fluid restriction significantly impaired endothelial function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.