Evidence map›Paper›PMID 26864087›Full record

ArticleChemical communications (Cambridge, England)2016

Quantitatively resolving multivalent interactions on a macroscopic scale using force spectroscopy.

Qiongzheng Hu, Haopeng Yang, Yuhong Wang, Shoujun Xu

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qiongzheng HuDepartment of Chemistry, University of Houston, Houston, TX 77204, USA. sxu7@uh.edu.
Haopeng YangDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA. ywang60@uh.edu.
Yuhong WangDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA. ywang60@uh.edu.
Shoujun XuDepartment of Chemistry, University of Houston, Houston, TX 77204, USA. sxu7@uh.edu.

Funding

EF-Tu mutagenesis and functional studyR01GM111452 · NIGMS · UNIVERSITY OF HOUSTON · PI YUHONG WANG, Shoujun Xu · 2015 to 2026
$3.2M
NIGMS NIH HHS R01 GM111452NIGMS NIH HHS R01GM111452
6 · The paper itself

Abstract

Multivalent interactions remain difficult to be characterized and consequently controlled, particularly on a macroscopic scale. Using force-induced remnant magnetization spectroscopy (FIRMS), we have resolved the single-, double-, and triple-biotin-streptavidin interactions, multivalent DNA interactions and CXCL12-CXCR4 interactions on millimetre-scale surfaces. Our results establish FIRMS as a viable method for systematic resolution and controlled formation of multivalent interactions.

Indexed as

Microscopy, Atomic ForceBiotinDNAStreptavidinBiotinDNAStreptavidin

Identifiers

PMID26864087
PMCPMC4767602

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.