Evidence map›Paper›PMID 26864054›Full record

ReviewThe British journal of radiology2016

Imaging genomics in cancer research: limitations and promises.

Harrison X Bai, Ashley M Lee, Li Yang, Paul Zhang, Christos Davatzikos, John M Maris, Sharon J Diskin

Abstract readReview
In one paragraph

Review in The British journal of radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed.

  1. Metastatic Colorectal Cancer Treatment Response Evaluation by Ultra-Deep Sequencing of Cell-Free DNA and Matched White Blood Cells.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Trial
  2. Trial
  3. Article
  4. Article
  5. The impact of radiogenomics on breast cancer.American journal of cancer research · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
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  12. Article
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  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Harrison X Bai1 Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Ashley M Lee1 Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Li Yang2 Department of Neurology, The Second Xiangya Hospital, Changsha, Hunan, China.
Paul Zhang3 Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Christos Davatzikos1 Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
John M Maris4 Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Sharon J Diskin4 Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Funding

Statistical atlases of brain tumor MRI:do imaging phenotypes predict progression?R01NS042645 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2002 to 2024
$8.7M
NINDS NIH HHS R01 NS042645
6 · The paper itself

Abstract

Recently, radiogenomics or imaging genomics has emerged as a novel high-throughput method of associating imaging features with genomic data. Radiogenomics has the potential to provide comprehensive intratumour, intertumour and peritumour information non-invasively. This review article summarizes the current state of radiogenomic research in tumour characterization, discusses some of its limitations and promises and projects its future directions. Semi-radiogenomic studies that relate specific gene expressions to imaging features will also be briefly reviewed.

Indexed as

Diagnostic ImagingGenomicsHumansNeoplasms

Identifiers

PMID26864054
PMCPMC4985482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.