ArticlePlant physiology2016
Homodimerization of Ehd1 Is Required to Induce Flowering in Rice.
Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed.
- Rice OsFKF1 Promotes Degradation of OsPRR37 for Short-Day Early Flowering.Rice (New York, N.Y.) · 2025Article
- Genomic Insights intoInternational journal of molecular sciences · 2025Article
- Root-derived cytokinin regulates Arabidopsis flowering time through components of the age pathway.Plant physiology · 2025Article
- Type-A and -C response regulator genes positively impact rice plant height and panicle architecture.Plant cell reports · 2025Article
- Non-Canonical Inter-Protein Interactions of Key Proteins Belonging to Cytokinin Signaling Pathways.Plants (Basel, Switzerland) · 2025Review
- Hormonal influence on maize inflorescence development and reproduction.Plant reproduction · 2024Review
- Sucrose induces flowering by degradation of the floral repressor Ghd7 via K48-linked polyubiquitination in rice.Journal of integrative plant biology · 2024Article
- Expression and functional divergence of a type-A response regulator paralog pair formed by dispersed duplication during Populus deltoides evolution.Communications biology · 2024Article
- Research Progress on Photoperiod Gene Regulation of Heading Date in Rice.Current issues in molecular biology · 2024Review
- Insights on physiological, antioxidant and flowering response to salinity stress of two candidate ornamental species: the native coastal geophytesPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- Rice Promoter Editing: An Efficient Genetic Improvement Strategy.Rice (New York, N.Y.) · 2024Review
- OsCOL5 suppresses heading through modulation of Ghd7 and Ehd2, enhancing rice yield.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Enhancing Yield and Improving Grain Quality in Japonica Rice: Targeted EHD1 Editing via CRISPR-Cas9 in Low-Latitude Adaptation.Current issues in molecular biology · 2024Article
- OsWRKY26 negatively regulates bacterial blight resistance by suppressingFrontiers in plant science · 2024Article
- Improving yield-related traits by editing the promoter of the heading date gene Ehd1 in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Quantitative Proteomic Analysis Deciphers the Molecular Mechanism for Endosperm Nuclear Division in Early Rice Seed Development.Plants (Basel, Switzerland) · 2023Article
- Deleterious mutations predicted in the sorghum (Sorghum bicolor) Maturity (Ma) and Dwarf (Dw) genes from whole-genome resequencing.Scientific reports · 2023Article
- Environmental control of rice flowering time.Plant communications · 2023Review
- Genomic basis of multiphase evolution driving divergent selection of zinc-finger homeodomain genes.Nucleic acids research · 2023Article
- Sucrose preferentially promotes expression ofFrontiers in plant science · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In plants, flowering time is elaborately controlled by various environment factors. Ultimately, florigens such as FLOWERING LOCUS T (FT) or FT-like molecules induce flowering. In rice (Oryza sativa), Early heading date 1 (Ehd1) is a major inducer of florigen gene expression. Although Ehd1 is highly homologous to the type-B response regulator (RR) family in the cytokinin signaling pathway, its precise molecular mechanism is not well understood. In this study, we showed that the C-terminal portion of the protein containing the GARP DNA-binding (G) domain can promote flowering when overexpressed. We also observed that the N-terminal portion of Ehd1, carrying the receiver (R) domain, delays flowering by inhibiting endogenous Ehd1 activity. Ehd1 protein forms a homomer via a 16-amino acid region in the inter domain between R and G. From the site-directed mutagenesis analyses, we demonstrated that phosphorylation of the Asp-63 residue within the R domain induces the homomerization of Ehd1, which is crucial for Ehd1 activity. A type-A RR, OsRR1, physically interacts with Ehd1 to form a heterodimer. In addition, OsRR1-overexpressing plants show a late-flowering phenotype. Based on these observations, we conclude that OsRR1 inhibits Ehd1 activity by binding to form an inactive complex.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.