Evidence map›Paper›PMID 26863280›Full record

ArticleDalton transactions (Cambridge, England : 2003)2016

Facile rhenium-peptide conjugate synthesis using a one-pot derived Re(CO)3 reagent.

Kullapa Chanawanno, Vinay Kondeti, Joel Caporoso, Sailaja Paruchuri, Thomas C Leeper, Richard S Herrick, Christopher J Ziegler

Abstract read
In one paragraph

Article in Dalton transactions (Cambridge, England : 2003), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Lipophilic Re(CO)Dalton transactions (Cambridge, England : 2003) · 2021
    Article
  2. Article
  3. Using Hydrazine to Link Ferrocene with Re(CO)Journal of organometallic chemistry · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Kullapa ChanawannoDepartment of Chemistry, University of Akron, OH 44325-3601, USA. ziegler@uakron.edu.
Vinay Kondeti
Joel Caporoso
Sailaja Paruchuri
Thomas C Leeper
Richard S Herrick
Christopher J Ziegler
University of Akron · USUniversity of Worcester · GB

Funding

The synthesis and screening of rhenium carbonyl compounds as technetium modelsR15GM083322 · NIGMS · UNIVERSITY OF AKRON · PI ZIEGLER, CHRISTOPHER J · 2009 to 2009
$223k
NIGMS NIH HHS R15 GM083322
6 · The paper itself

Abstract

We have synthesized two Re(CO)3-modified lysine complexes (1 and 2), where the metal is attached to the amino acid at the Nε position, via a one-pot Schiff base formation reaction. These compounds can be used in the solid phase synthesis of peptides, and to date we have produced four conjugate systems incorporating neurotensin, bombesin, leutenizing hormone releasing hormone, and a nuclear localization sequence. We observed uptake into human umbilical vascular endothelial cells as well as differential uptake depending on peptide sequence identity, as characterized by fluorescence and rhenium elemental analysis.

Indexed as

Cell SurvivalCoordination ComplexesHumansHuman Umbilical Vein Endothelial CellsMicroscopy, FluorescencePeptidesRheniumSchiff BasesSolid-Phase Synthesis TechniquesCoordination ComplexesPeptidesRheniumSchiff Bases

Identifiers

PMID26863280
PMCPMC4991029
OpenAlexW2289752073

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.