Evidence map›Paper›PMID 26863012›Full record

ArticlePloS one2016

Lactic Acid Production from Pretreated Hydrolysates of Corn Stover by a Newly Developed Bacillus coagulans Strain.

Ting Jiang, Hui Qiao, Zhaojuan Zheng, Qiulu Chu, Xin Li, Qiang Yong, Jia Ouyang

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 64 citations in OpenAlex.

  1. Nutrients · 2026
    Trial
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  13. Article
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  16. Transcriptomic analysis of the oleaginous yeastBiotechnology for biofuels · 2019
    Article
  17. Article
  18. Potential Use ofFoods (Basel, Switzerland) · 2018
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ting JiangCollege of Chemical Engineering, Nanjing Forestry University, Nanjing, 210037, People's Republic of China.
Hui QiaoCollege of Chemical Engineering, Nanjing Forestry University, Nanjing, 210037, People's Republic of China.
Zhaojuan ZhengCollege of Chemical Engineering, Nanjing Forestry University, Nanjing, 210037, People's Republic of China.
Qiulu ChuCollege of Chemical Engineering, Nanjing Forestry University, Nanjing, 210037, People's Republic of China.
Xin LiCollege of Chemical Engineering, Nanjing Forestry University, Nanjing, 210037, People's Republic of China.
Qiang YongKey Laboratory of Forest Genetics and Biotechnology of the Ministry of Education, Nanjing Forestry University, Nanjing, 210037, People's Republic of China.
Jia OuyangCollege of Chemical Engineering, Nanjing Forestry University, Nanjing, 210037, People's Republic of China.
Nanjing Forestry University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An inhibitor-tolerance strain, Bacillus coagulans GKN316, was developed through atmospheric and room temperature plasma (ARTP) mutation and evolution experiment in condensed dilute-acid hydrolysate (CDH) of corn stover. The fermentabilities of other hydrolysates with B. coagulans GKN316 and the parental strain B. coagulans NL01 were assessed. When using condensed acid-catalyzed steam-exploded hydrolysate (CASEH), condensed acid-catalyzed liquid hot water hydrolysate (CALH) and condensed acid-catalyzed sulfite hydrolysate (CASH) as substrates, the concentration of lactic acid reached 45.39, 16.83, and 18.71 g/L by B. coagulans GKN316, respectively. But for B. coagulans NL01, only CASEH could be directly fermented to produce 15.47 g/L lactic acid. The individual inhibitory effect of furfural, 5-hydroxymethylfurfural (HMF), vanillin, syringaldehyde and p-hydroxybenzaldehyde (pHBal) on xylose utilization by B. coagulans GKN316 was also studied. The strain B. coagulans GKN316 could effectively convert these toxic inhibitors to the less toxic corresponding alcohols in situ. These results suggested that B. coagulans GKN316 was well suited to production of lactic acid from undetoxified lignocellulosic hydrolysates.

Indexed as

Industrial MicrobiologyBacillusBenzaldehydesBiomassBioreactorsFermentationFuraldehydeGlucoseHydrolysisLactic AcidLigninMutationTemperatureWaterXyloseZea mays4-hydroxybenzaldehyde5-hydroxymethylfurfuralBenzaldehydesFuraldehydeGlucoseLactic AcidLigninsyringaldehydevanillinWaterXylose

Identifiers

PMID26863012
PMCPMC4749344
OpenAlexW2269539718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.