Evidence map›Paper›PMID 26862865›Full record

ArticleEnvironmental health perspectives2016

Ambient Fine Particulate Matter, Nitrogen Dioxide, and Preterm Birth in New York City.

Sarah Johnson, Jennifer F Bobb, Kazuhiko Ito, David A Savitz, Beth Elston, Jessie L C Shmool, Francesca Dominici, Zev Ross, Jane E Clougherty, Thomas Matte

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 5 pooled it
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 5 syntheses or guidelines pooled it, 88 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Sarah JohnsonNew York City Department of Health and Mental Hygiene, New York, New York, USA.
Jennifer F Bobb
Kazuhiko Ito
David A Savitz
Beth Elston
Jessie L C Shmool
Francesca Dominici
Zev Ross
Jane E Clougherty
Thomas Matte
New York City Department of Health and Mental Hygiene · USBrown University · USHarvard University · USUniversity of Pittsburgh · USIthaca College · US

Funding

GRADUATE TRAINING IN BIOSTATISTICST32ES007142 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Brent Andrew Coull · 1985 to 2026
$11.9M
Air Pollution and Pregnancy Outcome in New York CityR01ES019955 · NIEHS · BROWN UNIVERSITY · PI SAVITZ, DAVID A · 2011 to 2013
$1.3M
NIEHS NIH HHS R01 ES019955NIEHS NIH HHS T32 ES007142
6 · The paper itself

Abstract

backgroundRecent studies have suggested associations between air pollution and various birth outcomes, but the evidence for preterm birth is mixed.

objectiveWe aimed to assess the relationship between air pollution and preterm birth using 2008-2010 New York City (NYC) birth certificates linked to hospital records.

methodsWe analyzed 258,294 singleton births with 22-42 completed weeks gestation to nonsmoking mothers. Exposures to ambient fine particles (PM2.5) and nitrogen dioxide (NO2) during the first, second, and cumulative third trimesters within 300 m of maternal address were estimated using data from the NYC Community Air Survey and regulatory monitors. We estimated the odds ratio (OR) of spontaneous preterm (gestation < 37 weeks) births for the first- and second-trimester exposures in a logistic mixed model, and the third-trimester cumulative exposures in a discrete time survival model, adjusting for maternal characteristics and delivery hospital. Spatial and temporal components of estimated exposures were also separately analyzed.

resultsPM2.5 was not significantly associated with spontaneous preterm birth. NO2 in the second trimester was negatively associated with spontaneous preterm birth in the adjusted model (OR = 0.90; 95% CI: 0.83, 0.97 per 20 ppb). Neither pollutant was significantly associated with spontaneous preterm birth based on adjusted models of temporal exposures, whereas the spatial exposures showed significantly reduced odds ratios (OR = 0.80; 95% CI: 0.67, 0.96 per 10 μg/m3 PM2.5 and 0.88; 95% CI: 0.79, 0.98 per 20 ppb NO2). Without adjustment for hospital, these negative associations were stronger.

conclusionNeither PM2.5 nor NO2 was positively associated with spontaneous preterm delivery in NYC. Delivery hospital was an important spatial confounder. CITATION: Johnson S, Bobb JF, Ito K, Savitz DA, Elston B, Shmool JL, Dominici F, Ross Z, Clougherty JE, Matte T. 2016. Ambient fine particulate matter, nitrogen dioxide, and preterm birth in New York City. Environ Health Perspect 124:1283-1290; http://dx.doi.org/10.1289/ehp.1510266.

Indexed as

Air PollutantsAir PollutionBirth WeightEnvironmental ExposureFemaleHumansInfant, NewbornModels, TheoreticalNew York CityNitrogen DioxideParticulate MatterPregnancyPregnancy Trimester, SecondPremature BirthAir PollutantsNitrogen DioxideParticulate Matter

Identifiers

PMID26862865
PMCPMC4977049
OpenAlexW2413228989

What OpenQuestion holds

Textmetadata
LicenceCC0
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.