Evidence map›Paper›PMID 26862673›Full record

ReviewThe Pediatric infectious disease journal2016

Cytomegalovirus Enterocolitis in Immunocompetent Young Children: A Report of Two Cases and Review of the Literature.

Paul K Sue, Nicole M Salazar-Austin, Oliver G McDonald, Arvind Rishi, Toby C Cornish, Ravit Arav-Boger

Open access · greenAbstract readCase ReportsReview
In one paragraph

Review in The Pediatric infectious disease journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Children (Basel, Switzerland) · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Human inborn errors of immunity to herpes viruses.Current opinion in immunology · 2020
    Review
  11. Diagnosis and Management of CMV Colitis.Current infectious disease reports · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Paul K SueFrom the *Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Maryland; †Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas; ‡Division of Microbiology, Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland; §Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee; and ¶Department of Pathology, Hofstra Northwell School of Medicine, Lake Success, New York.
Nicole M Salazar-Austin
Oliver G McDonald
Arvind Rishi
Toby C Cornish
Ravit Arav-Boger
Development Fund · NOJohns Hopkins Hospital · USThe University of Texas Southwestern Medical Center · US

Funding

Research Training in Pediatric Infectious DiseasesT32AI052071 · NIAID · JOHNS HOPKINS UNIVERSITY · PI AARON M MILSTONE · 2002 to 2026
$5.2M
NIAID NIH HHS T32 AI052071PHS HHS R01 093701-04
6 · The paper itself

Abstract

Cytomegalovirus (CMV) causes significant morbidity and mortality in congenitally infected children and immunocompromised hosts. Among healthy individuals, CMV is generally thought to cause mild, self-limited illness. CMV enterocolitis, in particular, is rarely considered among immunocompetent children presenting with diarrhea. We describe 2 cases of invasive CMV colitis in immunocompetent infants presenting with diarrhea and review the literature to date on this topic. Although invasive CMV enterocolitis has been sporadically reported among immunocompetent children, it remains an underrecognized cause of infectious diarrhea in this population and indications for antiviral therapy are lacking. We propose that CMV should be included in the differential diagnosis of intractable diarrhea in immunocompetent children.

Indexed as

CytomegalovirusCytomegalovirus InfectionsDiarrheaEnterocolitisHumansInfantMale

Identifiers

PMID26862673
PMCPMC4829454
OpenAlexW2333221433

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.