ReviewWorld journal of clinical pediatrics2016
Clinical spectrum of primary ciliary dyskinesia in childhood.
Review in World journal of clinical pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Ear and upper airway clinical outcome measures for use in primary ciliary dyskinesia research: a scoping review.European respiratory review : an official journal of the European Respiratory Society · 2023Article
- Bronchiectasis Assessment in Primary Ciliary Dyskinesia: A Non-Invasive Approach Using Forced Oscillation Technique.Diagnostics (Basel, Switzerland) · 2023Article
- Reversible bronchiectasis caused by influenza virus mimicking Williams-Campbell syndrome.Pediatric radiology · 2022Article
- Otological Manifestations in Adults with Primary Ciliary Dyskinesia: A Controlled Radio-Clinical Study.Journal of clinical medicine · 2022Article
- The Genetics of Primary Ciliary Dyskinesia in Puerto Rico.Diagnostics (Basel, Switzerland) · 2022Article
- Pediatric Versus Adult Chronic Rhinosinusitis.Current allergy and asthma reports · 2020Review
- Epithelial cell function and remodeling in nasal polyposis.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2020Review
- Translation of the quality-of-life measure for adults with primary ciliary dyskinesia and its application in patients in Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2019Article
- Chronic Rhinosinusitis in Children: Pathophysiology, Evaluation, and Medical Management.Current allergy and asthma reports · 2018Review
- Variation in Cilia Protein Genes and Progression of Lung Disease in Cystic Fibrosis.Annals of the American Thoracic Society · 2018Observational
- Cilia distribution and polarity in the epithelial lining of the mouse middle ear cavity.Scientific reports · 2017Article
- Primary Ciliary Dyskinesia: An Update on Clinical Aspects, Genetics, Diagnosis, and Future Treatment Strategies.Frontiers in pediatrics · 2017Review
- Image Diagnosis: Multivessel Percutaneous Coronary Intervention in Dextrocardia: Success with Usual Techniques in a Case of Mirror-Image Heart.The Permanente journal · 2017Article
- The determination factors of left-right asymmetry disorders- a short review.Clujul medical (1957) · 2017Review
- Heterotaxy in Caenorhabditis: widespread natural variation in left-right arrangement of the major organs.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Article
- Review
- Repair of a juxtarenal abdominal aortic aneurysm in a patient with situs inversus totalis using a retroperitoneal approach.Journal of vascular surgery cases and innovative techniques · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the triad of bronchiectasis, sinusitis and situs inversus was first described by Kartagener in 1933, the clinical spectrum of primary ciliary dyskinesia is still under investigation. Heterotaxy defects as well as upper and lower respiratory tract symptoms are the main manifestations in childhood. It is now recognized that situs inversus is encountered in only half of patients. The first lower respiratory symptoms may be present from infancy as neonatal respiratory distress. The most common lower airway manifestations are chronic wet cough, recurrent pneumonia and therapy resistant wheezing. Patients are at risk of developing bronchiectasis which may even be the presenting finding due to delayed diagnosis. Upper respiratory tract infections such as nasal congestion, nasal drainage and recurrent sinusitis as well as otologic manifestations such as otitis media or otorrhea with conductive hearing loss are also often encountered. It seems that the type of ciliary ultrastructure defects and the involved mutated genes are associated to some extent to the clinical profile. The disease, even in nowadays, is not recognized at an early age and the primary care clinician should have knowledge of its clinical spectrum in order to select appropriately the children who need further investigation for the diagnosis of this disorder.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.